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Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells.
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scholarly article
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stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
title
Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells
(English)
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
main subject
cervix uterine cancer
1 reference
based on heuristic
inferred from title
author
Peter Howley
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
D A Francis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
S I Schmid
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
language of work or name
English
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publication date
1 March 2000
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Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
74
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
2679-2686
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
issue
6
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
cites work
Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition
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PubMed Central
reference URL
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4 July 2018
Bovine papillomavirus E2 protein activates a complex growth-inhibitory program in p53-negative HT-3 cervical carcinoma cells that includes repression of cyclin A and cdc25A phosphatase genes and accumulation of hypophosphorylated retinoblastoma prot
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines
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PubMed Central
reference URL
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4 July 2018
Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control.
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PubMed Central
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4 July 2018
Functional interaction of the bovine papillomavirus E2 transactivation domain with TFIIB.
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4 July 2018
Functional interaction of a novel cellular protein with the papillomavirus E2 transactivation domain
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PubMed Central
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4 July 2018
Conserved interaction of the papillomavirus E2 transcriptional activator proteins with human and yeast TFIIB proteins.
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PubMed Central
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4 July 2018
Interactions of the human papillomavirus E7 protein with cell cycle regulators
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Enhanced transcriptional activation by E2 proteins from the oncogenic human papillomaviruses
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Papillomavirus infections--a major cause of human cancers
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The E2 transcriptional repressor can compensate for Sp1 activation of the human papillomavirus type 18 early promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Low-affinity E2-binding site mediates downmodulation of E2 transactivation of the human papillomavirus type 8 late promoter.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Bovine papillomavirus type 1 E2 transcriptional regulators directly bind two cellular transcription factors, TFIID and TFIIB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Suppression of cellular proliferation by the papillomavirus E2 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
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4 July 2018
Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
p53 functions as a cell cycle control protein in osteosarcomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Cooperative activation of transcription by bovine papillomavirus type 1 E2 can occur over a large distance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Association of human papillomavirus types 16 and 18 E6 proteins with p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Functional analysis of E2-mediated repression of the HPV18 P105 promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Mechanism of action of the papillomavirus E2 repressor: repression in the absence of DNA binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111757
retrieved
4 July 2018
Activation of the endogenous p53 growth inhibitory pathway in HeLa cervical carcinoma cells by expression of the bovine papillomavirus E2 gene
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10684283
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The physical state of human papillomavirus type 16 DNA in benign and malignant genital tumours
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10684283
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/JVI.74.6.2679-2686.2000
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
PMCID
111757
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
PubMed ID
10684283
1 reference
stated in
Europe PubMed Central
PMCID
111757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10684283%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
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