(Q33806957)

English

Single cell mutational analysis of PIK3CA in circulating tumor cells and metastases in breast cancer reveals heterogeneity, discordance, and mutation persistence in cultured disseminated tumor cells from bone marrow

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Single cell mutational analysis of PIK3CA in circulating tumor cells and metastases in breast cancer reveals heterogeneity, discordance, and mutation persistence in cultured disseminated tumor cells from bone marrow (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

mutational analysis

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Stefanie S Jeffrey

8

object named as

Stefanie S Jeffrey

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Glenn Deng

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Sujatha Krishnakumar

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ashley A Powell

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Haiyu Zhang

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Michael N Mindrinos

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Melinda L Telli

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ronald W Davis

7

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Europe PubMed Central

PubMed publication ID

29 July 2017

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publication date

19 June 2014

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

456

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Circulating tumor cells and response to chemotherapy in metastatic breast cancer: SWOG S0500

1 reference

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Recent advances in the molecular characterization of circulating tumor cells

1 reference

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Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials

1 reference

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28 July 2018

Tumor heterogeneity in the clinic: is it a real problem?

1 reference

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Single cell analysis of cancer genomes

1 reference

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Circulating tumor cells: exploring intratumor heterogeneity of colorectal cancer

1 reference

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28 July 2018

Reliable single cell array CGH for clinical samples

1 reference

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28 July 2018

Molecular analysis of circulating tumour cells-biology and biomarkers

1 reference

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Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors

1 reference

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28 July 2018

KRAS mutational status analysis of peripheral blood isolated circulating tumor cells in metastatic colorectal patients.

1 reference

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Mutational Analysis of Circulating Tumor Cells Using a Novel Microfluidic Collection Device and qPCR Assay

1 reference

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Technologies for detection of circulating tumor cells: facts and vision

1 reference

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Real-time liquid biopsy in cancer patients: fact or fiction?

1 reference

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28 July 2018

Analysing the mutational status of PIK3CA in circulating tumor cells from metastatic breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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The identification and characterization of breast cancer CTCs competent for brain metastasis

1 reference

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Detection and recovery of circulating colon cancer cells using a dielectrophoresis-based device: KRAS mutation status in pure CTCs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Cancer heterogeneity: implications for targeted therapeutics

1 reference

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Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue

1 reference

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28 July 2018

Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients

1 reference

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Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials

1 reference

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28 July 2018

Comprehensive molecular portraits of human breast tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Detection of tumor PIK3CA status in metastatic breast cancer using peripheral blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Clinical relevance and biology of circulating tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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New driver mutations in non-small-cell lung cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

PIK3CA Mutations May Be Discordant between Primary and Corresponding Metastatic Disease in Breast Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

PIK3CA mutation associates with improved outcome in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

28 July 2018

Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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Enrichment with anti-cytokeratin alone or combined with anti-EpCAM antibodies significantly increases the sensitivity for circulating tumor cell detection in metastatic breast cancer patients

1 reference

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1 reference

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1 reference

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Somatic mutation and gain of copy number of PIK3CA in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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Circulating tumor cells, disease progression, and survival in metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071027

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Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-456

21 January 2018

Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-456

21 January 2018

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

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Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing

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The role and clinical relevance of disseminated tumor cells in breast cancer

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Next-generation sequencing of disseminated tumor cells

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Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-456

21 January 2018

Mutational hotspot in exon 20 of PIK3CA in breast cancer among Singapore Chinese.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-456

21 January 2018

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

1 reference

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21 January 2018

Discordance between K-ras mutations in bone marrow micrometastases and the primary tumor in colorectal cancer.

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Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.

1 reference

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21 January 2018

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-456

21 January 2018

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Erratum: Integrated genomic analyses of ovarian carcinoma

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Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24947048

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Detection and viability of tumor cells in peripheral blood stem cell collections from breast cancer patients using immunocytochemical and clonogenic assay techniques

1 reference

https://pubmed.ncbi.nlm.nih.gov/24947048

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24947048

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2407-14-456

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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