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The third function of the thymus.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
The third function of the thymus
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author
Benedict Seddon
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
D Mason
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 February 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Trends in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
21
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
95-99
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
A very high level of crossreactivity is an essential feature of the T-cell receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic mechanisms and therapy in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+CD8- thymocytes that express L-selectin protect rats from diabetes upon adoptive transfer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interception of the development of self tolerance in fetal lambs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral autoantigen induces regulatory T cells that prevent autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anergic T cells effect linked suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anergic T cells actively suppress T cell responses via the antigen-presenting cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta (TGF-beta)-dependent inhibition of T helper cell 2 (Th2)-induced autoimmunity by self-major histocompatibility complex (MHC) class II-specific, regulatory CD4(+) T cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oral tolerance: immune mechanisms and treatment of autoimmune diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of interleukin-10 on dendritic cell maturation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Th1 cells induce and Th2 inhibit antigen-dependent IL-12 secretion by dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How do monoclonal antibodies induce tolerance? A role for infectious tolerance?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infectious tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T-cell subsets in autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of immune pathology by regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901559-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-5699(99)01559-5
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed ID
10652468
1 reference
stated in
Europe PubMed Central
PubMed ID
10652468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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