(Q33855160)

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Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice.

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21 January 2020

Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice (English)

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21 January 2020

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21 January 2020

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Yung-Feng Lin

1

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21 January 2020

Austin Cape

3

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21 January 2020

Shihua Li

4

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21 January 2020

Xiao-Jiang Li

5

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21 January 2020

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19 March 2010

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21 January 2020

Journal of Biological Chemistry

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21 January 2020

285

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21 January 2020

21

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21 January 2020

15941-15949

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20304926%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin as an essential integrator of intracellular vesicular trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

The brain hypocretins and their receptors: mediators of allostatic arousal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

A role for brain stress systems in addiction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

HAP1 and intracellular trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Mutations in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Distribution of orexin neurons in the adult rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Neurons containing hypocretin (orexin) project to multiple neuronal systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Interaction of huntingtin-associated protein with dynactin P150Glued

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

28 July 2018

Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

The dorsomedial hypothalamic nucleus and its role in ingestive behavior and body weight regulation: lessons learned from lesioning studies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Postnatal development of orexin/hypocretin in rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Developmental and aging change of orexin-A and -B immunoreactive neurons in the male rat hypothalamus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Differences in the appetite-stimulating effect of orexin, neuropeptide Y and ghrelin among young, adult and old rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Diminished feeding responsiveness to orexin A (hypocretin 1) in aged rats is accompanied by decreased neuronal activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107318

21 January 2018

Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871462

29 October 2018

Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20304926

12 December 2020

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10.1074/JBC.M110.107318

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20304926%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20304926%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20304926%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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