(Q33884776)

29 July 2017

Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway (English)

1 reference

29 July 2017

R J Lee

1

1 reference

29 July 2017

C Albanese

2

1 reference

29 July 2017

M Fu

3

1 reference

29 July 2017

M D'Amico

4

1 reference

29 July 2017

B Lin

5

1 reference

29 July 2017

G Watanabe

6

1 reference

29 July 2017

G K Haines

7

1 reference

29 July 2017

P M Siegel

8

1 reference

29 July 2017

M C Hung

9

1 reference

29 July 2017

Y Yarden

10

1 reference

29 July 2017

J M Horowitz

11

1 reference

29 July 2017

W J Muller

12

1 reference

29 July 2017

R G Pestell

13

1 reference

29 July 2017

language of work or name

English

0 references

publication date

1 January 2000

1 reference

Molecular and Cellular Biology

29 July 2017

1 reference

29 July 2017

20

1 reference

29 July 2017

672-683

1 reference

29 July 2017

2

1 reference

describes a project that uses

29 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC85165/fullTextXML

inferred from PubMed Central ID database lookup

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5 July 2018

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

5 July 2018

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pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1.

5 July 2018

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Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation

5 July 2018

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Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes.

5 July 2018

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A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase

5 July 2018

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Subunit composition determines E2F DNA-binding site specificity

5 July 2018

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Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

5 July 2018

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Role of cyclins in neuronal differentiation of immortalized hippocampal cells

5 July 2018

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Rho GTPases and signaling networks

5 July 2018

1 reference

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Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4

5 July 2018

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A cytoplasmic inhibitor of the JNK signal transduction pathway

5 July 2018

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Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

5 July 2018

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Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

5 July 2018

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p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression

5 July 2018

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Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint

5 July 2018

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5 July 2018

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Induction of cyclin D1 by simian virus 40 small tumor antigen

5 July 2018

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Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1

5 July 2018

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Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cells

5 July 2018

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p70 S6 kinase: an enigma with variations

5 July 2018

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Angiotensin II activation of cyclin D1-dependent kinase activity

5 July 2018

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Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

5 July 2018

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Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions

5 July 2018

1 reference

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Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

5 July 2018

1 reference

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Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F

5 July 2018

1 reference

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The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

5 July 2018

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E2F and cell proliferation: a world turned upside down

5 July 2018

1 reference

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Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit

5 July 2018

1 reference

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Activated neu induces rapid tumor progression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

A role for Rho in Ras transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Biological assays for Ras transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Neu and its ligands: from an oncogene to neural factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

neu(c-erbB-2/HER2) and the epidermal growth factor receptor (EGFR) in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Multiple members of the E2F transcription factor family are the products of oncogenes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Intermolecular association and trans-phosphorylation of different neu-kinase forms permit SH2-dependent signaling and oncogenic transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Different roles for cyclins D1 and E in regulation of the G1-to-S transition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Tyrosine phosphorylation of Shc proteins and formation of Shc/Grb2 complex correlate to the transformation of NIH3T3 cells mediated by the point-mutation activated neu.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

The retinoblastoma protein and cell cycle control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

An essential role for Rac in Ras transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Overexpression of erbB-2 or EGF receptor proteins present in early stage mammary carcinoma is detected simultaneously in matched primary tumors and regional metastases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Mapping protein-DNA interactions in vivo with formaldehyde: evidence that histone H4 is retained on a highly transcribed gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

The binding of transcription factor Sp1 to multiple sites is required for maximal expression from the rat transforming growth factor alpha promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

High gradient magnetic cell separation with MACS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85165

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

29 October 2018

1 reference

12 December 2020

Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies

1 reference

12 December 2020

D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1

1 reference

12 December 2020

Cyclin D1 protein expression and function in human breast cancer

1 reference

12 December 2020

10.1128/MCB.20.2.672-683.2000

Identifiers

DOI

1 reference

release_5rfev3mc7rfqzied6lolt2fiki

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5rfev3mc7rfqzied6lolt2fiki

24 November 2022

mapped directly with Wikidata item

PMCID

85165

1 reference

29 July 2017

1 reference