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Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo.
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
main subject
cytotoxicity
0 references
author
Joseph A. Trapani
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Mark J. Smyth
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
J Davis
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
V R Sutton
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
publication date
1 June 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
12
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
323-329
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual mechanisms of apoptosis induction by cytotoxic lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perforin-mediated myocardial damage in acute myocarditis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A natural killer cell granule protein that induces DNA fragmentation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New Paradigm for Lymphocyte Granule-mediated Cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antimicrobial activity of cytolytic T cells mediated by granulysin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTL granules: evolution of vesicles essential for combating virus infections
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perforin is essential for control of ectromelia virus but not related poxviruses in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme A initiates an alternative pathway for granule-mediated apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid on/off cycling of cytokine production by virus-specific CD8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homeostatic regulation of CD8+ T cells by perforin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perforin gene defects in familial hemophagocytic lymphohistiocytosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased tumor surveillance in perforin-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas ligand: a sensor for DNA damage critical in skin cancer etiology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900094-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(00)00094-7
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Fatcat ID
release_ngdq5hbm7nba5lshgrci36r2ee
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/ngdq5hbm7nba5lshgrci36r2ee
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
10781403
1 reference
stated in
Europe PubMed Central
PubMed ID
10781403
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10781403%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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