(Q33922356)

30 July 2017

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title

Essential fatty acids and the brain: possible health implications (English)

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30 July 2017

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Youdim KA

1

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30 July 2017

Martin A

series ordinal

2

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30 July 2017

Joseph JA

series ordinal

3

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30 July 2017

publication date

1 July 2000

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International Journal of Developmental Neuroscience

30 July 2017

published in

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30 July 2017

volume

18

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30 July 2017

issue

4-5

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30 July 2017

page(s)

383-399

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Effects of docosahexaenoic and eicosapentaenoic acid on lipid metabolism, eicosanoid production, platelet aggregation and atherosclerosis in hypercholesterolemic rats

30 July 2017

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7 January 2021

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7 January 2021

Accretion of n-3 fatty acids in the brain and retina of chicks fed a low-linolenic acid diet supplemented with docosahexaenoic acid

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7 January 2021

Efficacy of gamma-linolenic acid in the treatment of patients with atopic dermatitis

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7 January 2021

Localization of 12-lipoxygenase mRNA in cultured oligodendrocytes and astrocytes by in situ reverse transcriptase and polymerase chain reaction

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7 January 2021

Dietary menhaden and corn oils and the red blood cell membrane lipid composition and fluidity in hyper- and normocholesterolemic miniature swine

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7 January 2021

Inositol trisphosphate and calcium signalling

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7 January 2021

5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones

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7 January 2021

γ-Linolenic acid dietary supplementation can reverse the aging influence on rat liver microsome Δ6-desaturase activity

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7 January 2021

Delta 5-desaturation of dihomogammalinolenic acid (20:3(n-6)) into arachidonic acid (20:4(n-6)) by rat liver microsomes and incorporation of fatty acids in microsome phospholipids

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7 January 2021

Dietary alpha-linolenic acid deficiency in adult rats for 7 months does not alter brain docosahexaenoic acid content, in contrast to liver, heart and testes

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7 January 2021

Effect of increasing amounts of dietary fish oil on brain and liver fatty composition

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7 January 2021

Delta 6 desaturase in brain and liver during development and aging

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7 January 2021

Dietary linoleic acid and polyunsaturated fatty acids in rat brain and other organs. Minimal requirements of linoleic acid

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https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Modulators of leukotriene biosynthesis and receptor activation

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https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Low-dose eicosapentaenoic or docosahexaenoic acid administration modifies fatty acid composition and does not affect susceptibility to oxidative stress in rat erythrocytes and tissues

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https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Relationship between spermatozoan lipid composition and fertility during aging of chickens

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7 January 2021

Dietary fish oil affects monoaminergic neurotransmission and behavior in rats

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7 January 2021

The relationship of aging to endotoxin shock and to production of TNF-alpha

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7 January 2021

Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice

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https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Aging and the biophysical properties of cell membranes

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https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of dietary fatty acids on delta 5 desaturase activity and biosynthesis of arachidonic acid in rat liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

A comparison of the effects of linolenic (18:3 omega 3) and docosahexaenoic (22:6 omega 3) acids on phospholipid bilayers

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Importance of dietary gamma-linolenic acid in human health and nutrition

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of dietary polyunsaturated fatty acids on neuronal function

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of prostacyclin PGI2 on cardiopulmonary bypass-induced lung injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of essential fatty acid deficiency on myelin and various subcellular structures in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Delta 6-desaturase activity in liver microsomes of rats fed diets enriched with cholesterol and/or omega 3 fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Ambroxol inhibits the release of histamine, leukotrienes and cytokines from human leukocytes and mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of dipalmitoylglycerol and fatty acids on membrane structure and protein kinase C activity

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Regulation of the immune response by prostaglandins

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

n-3 and n-6 fatty acid enrichment by dietary fish oil and phospholipid sources in brain cortical areas and nonneural tissues of formula-fed piglets

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory-based and spatial learning tasks

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Hypothesis: are fatty acid patterns characteristic of essential fatty acid deficiency indicative of oxidative stress?

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Early neurogenesis in Xenopus: the spatio-temporal pattern of proliferation and cell lineages in the embryonic spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Role of arachidonic acid and other free fatty acids in mitochondrial dysfunction in brain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of dietary linoleic, alpha-linolenic and arachidonic acids on lipid metabolism, tissue fatty acid composition and eicosanoid production in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of docosahexaenoic and arachidonic acids on the synthesis and distribution of aminophospholipids during neuronal differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Membrane fatty acid modifications of PC12 cells by arachidonate or docosahexaenoate affect neurite outgrowth but not norepinephrine release

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Stability of the brain fatty acid pattern in adult rats during extreme starvation

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Evidence for the involvement of docosahexaenoic acid in cholinergic stimulated signal transduction at the synapse

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Reproterol--A monomolecular combination of orciprenaline and theophylline: novel aspects of its mode of action in asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Small changes of dietary (n-6) and (n-3)/fatty acid content ration alter phosphatidylethanolamine and phosphatidylcholine fatty acid composition during development of neuronal and glial cells in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary saturated fatty acids and brain function

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Delayed administration of ethyl eicosapentate improves local cerebral blood flow and metabolism without affecting infarct volumes in the rat focal ischemic model

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

cDNA cloning of a thromboxane A2 receptor from rat astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Changes in food and nutrient intake in middle-aged men from 1960 to 1985 (the Zutphen Study).

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of fish oil supplementation on acute ischemic brain injury in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

A possible essential role for dietary linolenic acid in the development of the young rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Modulation of membrane phospholipid fatty acid composition by age and food restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Age-associated changes in the content and fatty acid composition of brain glycerophospholipids

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Brain neutral lipids and phospholipids are modified by long-term feeding of beef tallow vs. corn oil diets

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of dietary fats on desaturase activities and the biosynthesis of fatty acids in rat-liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Oxidative stress hypothesis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Changes in dietary fatty acids alter phospholipid fatty acid composition in selected regions of rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth cones of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Changing fatty acid content of growth cone lipids prior to synaptogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of Oxidative Stress on Membrane Structure: Small-Angle X-Ray Diffraction Analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Leukotrienes: biosynthesis, metabolism, and pathophysiologic significance

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary fat composition and age affect synaptosomal and retinal phospholipid fatty acid composition in C57BL/6 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary docosahexaenoic acid increases cerebral acetylcholine levels and improves passive avoidance performance in stroke-prone spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary essential fatty acid deficiency differentially affects tissues of rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Diets enriched in menhaden fish oil, seal oil, or shark liver oil have distinct effects on the lipid and fatty-acid composition of guinea pig heart

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

The effects of purified eicosapentaenoic and docosahexaenoic acids on arterial thrombosis tendency and platelet function in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Changes in the fatty acid patterns of brain phospholipids during development of rats fed peanut or rapeseed oil, taking into account differences between milk and maternal food

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary polyunsaturated fatty acids, vitamin E and hypoxia/reoxygenation-induced damage to cardiac tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Minimum requirements of n-3 and n-6 essential fatty acids for the function of the central nervous system and for the prevention of chronic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of dietary fish oil on coronary artery and aortic atherosclerosis in African green monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Iron-Mediated Generation of the Neurotoxin 6-Hydroxydopamine Quinone by Reaction of Fatty Acid Hydroperoxides with Dopamine: A Possible Contributory Mechanism for Neuronal Degeneration in Parkinson's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Regional membrane phospholipid alterations in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Differential inhibitory mechanism of cyclic AMP on TNF-alpha and IL-12 synthesis by macrophages exposed to microbial stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Light elicits the release of docosahexaenoic acid from membrane phospholipids in the rat retina in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Liver microsomal mixed-function oxidases in response to polyunsaturated/saturated and n-6/n-3 fatty acid ratios of dietary lipids in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

The nervous system has an absolute molecular species requirement for proper function

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Arachidonic acid cascade and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Oxidative stress in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Purslane: a terrestrial source of omega-3 fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Polyunsaturation in cell membranes and lipid bilayers and its effects on membrane proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Interactions between the metabolism of n-3 and n-6 fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Influence of dietary fat on the activities of subcellular membrane-bound enzymes from different regions of rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Sodium transport kinetics, cell membrane lipid composition, neural conduction and metabolic control in type 1 diabetic patients. Changes after a low-dose n-3 fatty acid dietary intervention

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Docosahexaenoic acid increases permeability of lipid vesicles and tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of docosahexaenoic acid on mouse mitochondrial membrane properties

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid composition of brain stem phospholipids and synaptic membrane fluidity in adult mice: a comparison of sardine oil diet with palm oil diet

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

The fatty acid composition of subcellular membranes of rat liver, heart, and brain: diet-induced modifications

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary requirements and functions of α-linolenic acid in animals

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Linolenic acid deficiency: Changes in fatty acid patterns in female and male rats raised on a linolenic acid-deficient diet for two generations

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Oxidative stress effect on the integrity of lipid bilayers is modulated by cholesterol level of bilayers

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Leukotriene C4- and D4-induced diffuse peripheral constriction of swine coronary artery accompanied by ST elevation on the electrocardiogram: angiographic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Involvement of leukotriene B4 in murine dermatitis models

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effect of a high alpha-linolenate and high linoleate diet on membrane-associated enzyme activities in rat brain--modulation of Na+, K+- ATPase activity at suboptimal concentrations of ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Aging and oxidative stress in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Essential fatty acid status during early human development

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Increased thromboxane biosynthesis is associated with poststroke dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of dietary n-6 and n-3 lipids on antioxidant defense system in livers of exercised rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Water maze performance is unaffected in artificially reared rats fed diets supplemented with arachidonic acid and docosahexaenoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Oxidative damage in fetal rat brain induced by ischemia and subsequent reperfusion. Relation to arachidonic acid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary manipulation of long‐chain polyunsaturated fatty acids in the retina and brain of guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Dietary polyunsaturated fat decreases coronary artery atherosclerosis in a pediatric-aged population of African green monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Cytokine production in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Effects of a High-Linoleate and a High- -Linolenate Diet on the Learning Ability of Aged Rats Evidence Against an Autoxidation-Related Lipid Peroxide Theory of Aging

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

Beneficial effects of thyme oil on age-related changes in the phospholipid C20 and C22 polyunsaturated fatty acid composition of various rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

The effects of essential fatty acids preparation in the treatment of intrauterine growth retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0736-5748%2800%2900013-7

7 January 2021

10.1016/S0736-5748(00)00013-7

Identifiers

DOI

1 reference

30 July 2017

1 reference