(Q33929489)

30 July 2017

CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation (English)

1 reference

Chaperone ATPase HSP104 YLL026W

30 July 2017

0 references

1 reference

GOA release 2020-03-11

author name string

Sukyeong Lee

1

1 reference

30 July 2017

Bernhard Sielaff

2

1 reference

30 July 2017

Jungsoon Lee

3

1 reference

30 July 2017

Francis T F Tsai

4

1 reference

30 July 2017

language of work or name

English

0 references

publication date

19 April 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

107

1 reference

30 July 2017

8135-8140

1 reference

30 July 2017

18

1 reference

Motor mechanism for protein threading through Hsp104.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Hsp104 and ClpB: protein disaggregating machines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Peptide and protein binding in the axial channel of Hsp104. Insights into the mechanism of protein unfolding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Evolutionary relationships and structural mechanisms of AAA+ proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

The molecular chaperone Hsp104--a molecular machine for protein disaggregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

AAA+ proteins: have engine, will work

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Nucleotide dependent motion and mechanism of action of p97/VCP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

UCSF Chimera--a visualization system for exploratory research and analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

ClpS, a substrate modulator of the ClpAP machine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Structure of the AAA ATPase p97

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

EMAN: semiautomated software for high-resolution single-particle reconstructions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Protein disaggregation mediated by heat-shock protein Hsp104.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889573

Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Roles of individual domains and conserved motifs of the AAA+ chaperone ClpB in oligomerization, ATP hydrolysis, and chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

M domains couple the ClpB threading motor with the DnaK chaperone activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Modeling AAA+ ring complexes from monomeric structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

ATP binding to nucleotide binding domain (NBD)1 of the ClpB chaperone induces motion of the long coiled-coil, stabilizes the hexamer, and activates NBD2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Conformational properties of aggregated polypeptides determine ClpB-dependence in the disaggregation process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003572107

Saccharomyces cerevisiae Hsp104 protein. Purification and characterization of ATP-induced structural changes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20404203

12 December 2020

inferred from PubMed ID database lookup

Processing of proteins by the molecular chaperone Hsp104

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20404203

12 December 2020

inferred from PubMed ID database lookup

A 11.5 A single particle reconstruction of GroEL using EMAN

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20404203

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1003572107

1 reference

release_tjywaccimrb6bpsafq4i3oguqq

30 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tjywaccimrb6bpsafq4i3oguqq

24 November 2022

mapped directly with Wikidata item

PMCID

2889573

1 reference

30 July 2017

1 reference