(Q33933528)

English

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

30 July 2017

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway (English)

1 reference

Europe PubMed Central

30 July 2017

1 reference

based on heuristic

inferred from title

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

8

1 reference

Europe PubMed Central

30 July 2017

9

object named as

Tomlinson IP

1 reference

Europe PubMed Central

30 July 2017

K L Woodford-Richens

1

object named as

Woodford-Richens KL

1 reference

Europe PubMed Central

30 July 2017

author name string

Rowan AJ

2

1 reference

Europe PubMed Central

30 July 2017

Gorman P

3

1 reference

Europe PubMed Central

30 July 2017

Halford S

4

1 reference

Europe PubMed Central

30 July 2017

Bicknell DC

5

1 reference

Europe PubMed Central

30 July 2017

Wasan HS

6

1 reference

Europe PubMed Central

30 July 2017

Roylance RR

7

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

31 July 2001

1 reference

Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

30 July 2017

98

1 reference

Europe PubMed Central

30 July 2017

9719-9723

1 reference

Europe PubMed Central

30 July 2017

17

1 reference

Europe PubMed Central

30 July 2017

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

No SMAD4 hypermethylation in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Role of transforming growth factor-beta signaling in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Comparative genomic hybridisation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

DPC4/SMAD4 gene alterations in human cancer, and their functional implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

A structural basis for mutational inactivation of the tumour suppressor Smad4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Mad-related genes in the human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

A genetic model for colorectal tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Molecular genetics of colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

5 July 2018

Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patients.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171321498

21 January 2018

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171321498

21 January 2018

Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171321498

21 January 2018

Genetic pathways in the evolution of morphologically distinct colorectal neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

29 October 2018

Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55519

29 October 2018

Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4

1 reference

https://pubmed.ncbi.nlm.nih.gov/11481457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/11481457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic alterations of the DPC4 gene in human colorectal cancers in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11481457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11481457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homozygous deletion map at 18q21.1 in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11481457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/11481457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.171321498

1 reference

Europe PubMed Central

30 July 2017

2001PNAS...98.9719W

0 references

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33933528&oldid=1755010560"