(Q33934571)

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A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression (English)

1 reference

Europe PubMed Central

30 July 2017

8

object named as

Tasuku Honjo

1 reference

Europe PubMed Central

30 July 2017

object named as

Il-Mi Okazaki

2

0 references

object named as

Hirohisa Saito

7

0 references

Masamichi Muramatsu

3

object named as

Masamichi Muramatsu

1 reference

Europe PubMed Central

30 July 2017

author name string

Ai Kotani

1

1 reference

Europe PubMed Central

30 July 2017

Kazuo Kinoshita

4

1 reference

Europe PubMed Central

30 July 2017

Nasim A Begum

5

1 reference

Europe PubMed Central

30 July 2017

Toshiharu Nakajima

6

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

14 March 2005

1 reference

Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

30 July 2017

102

1 reference

Europe PubMed Central

30 July 2017

4506-4511

1 reference

Europe PubMed Central

30 July 2017

12

1 reference

Europe PubMed Central

30 July 2017

Detection and possible prognostic relevance of p53 gene mutations in diffuse large B-cell lymphoma. An analysis of 51 cases and review of the literature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Genome-wide somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

The regulation of somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Peripheral T-cell lymphomas: diagnosis and management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Mfold web server for nucleic acid folding and hybridization prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Regulation of early lymphocyte development by E2A family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Regulation of E2A activities by histone acetyltransferases in B lymphocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Somatic hypermutation of the AID transgene in B and non-B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

AID is essential for immunoglobulin V gene conversion in a cultured B cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

The TRANSFAC system on gene expression regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

E2A proteins: essential regulators at multiple stages of B-cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Somatic hypermutation of immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Localization of E2A mRNA expression in developing and adult rat tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Patterns of somatic mutations in immunoglobulin variable genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

The primary structure of the putative oncogene pim-1 shows extensive homology with protein kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Analysis of somatic mutations in kappa transgenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555529

5 July 2018

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

Separate domains of AID are required for somatic hypermutation and class-switch recombination

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

Constitutive expression of AID leads to tumorigenesis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

Identification of granulocyte subtype-selective receptors and ion channels by using a high-density oligonucleotide probe array.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

p53 gene mutations are associated with poor survival in low and low-intermediate risk diffuse large B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

Expression of the AID protein in normal and neoplastic B cells

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500830102

21 January 2018

The PU.1 and NF-EM5 binding motifs in the Igkappa 3' enhancer are responsible for directing somatic hypermutations to the intrinsic hotspots in the transgenic Vkappa gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary mediastinal B-cell lymphoma: hypermutation of the BCL6 gene targets motifs different from those in diffuse large B-cell and follicular lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clustered mutations in the transcriptional activation domain of Myc in 8q24 translocated lymphomas and their functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sequences from downstream of the J kappa cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0500830102

1 reference

Europe PubMed Central

30 July 2017

2005PNAS..102.4506K

0 references

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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