(Q33941417)

30 July 2017

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title

Complex roles of Stat1 in regulating gene expression (English)

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30 July 2017

Ramana CV

1

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30 July 2017

Chatterjee-Kishore M

series ordinal

2

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30 July 2017

Nguyen H

series ordinal

3

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30 July 2017

Stark GR

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

1 May 2000

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30 July 2017

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30 July 2017

19

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30 July 2017

2619-2627

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30 July 2017

21

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203525

30 July 2017

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cites work

Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-gamma inhibits thyrotropin-induced thyroidal peroxidase gene expression in cultured human thyrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Three-dimensional structure of the Stat3beta homodimer bound to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Deregulated expression of the c-myc oncogene abolishes inhibition of proliferation of rat vascular smooth muscle cells by serum reduction, interferon-gamma, heparin, and cyclic nucleotide analogues and induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Different requirements for signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 in the regulation of low molecular mass polypeptide 2 and transporter associated with antigen processing 1 gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Participation of JAK and STAT proteins in growth hormone-induced signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

JAK2 and STAT5, but not JAK1 and STAT1, are required for prolactin-induced beta-lactoglobulin transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcriptional suppression of rat angiotensin AT1a receptor gene expression by interferon-gamma in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcription factors induced by interferons alpha and gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

EGF induces nuclear translocation of STAT2 without tyrosine phosphorylation in intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

IFNgamma inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21WAF1/CIP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcription factor-specific requirements for coactivators and their acetyltransferase functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interaction between the components of the interferon gamma receptor complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Gamma-interferon activates a nuclear protein that binds to the gamma-interferon activation site of the thyroglobulin gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Regulation of STAT-dependent pathways by growth factors and cytokines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcriptional inhibition of stromelysin by interferon-gamma in normal human fibroblasts is mediated by the AP-1 domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Cooperative binding of Stat1-2 heterodimers and ISGF3 to tandem DNA elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Stat1 depends on transcriptional synergy with Sp1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon induction of TAP1: the phosphatase SHP-1 regulates crossover between the IFN-alpha/beta and the IFN-gamma signal-transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Tumor necrosis factor-alpha and interferon-gamma suppress both gene expression and deoxyribonucleic acid-binding of TTF-2 in FRTL-5 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-gamma suppresses thyrotropin receptor promoter activity by reducing thyroid transcription factor-1 (TTF-1) binding to its recognition site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Transcriptional silencing of perlecan gene expression by interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

The p300/CBP family: integrating signals with transcription factors and chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-gamma-mediated inhibition of cyclin A gene transcription is independent of individual cis-acting elements in the cyclin A promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-gamma-mediated inactivation of transcription of the 230-kDa bullous pemphigoid antigen gene (BPAG1) provides novel insight into keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Co-activators and co-repressors in the integration of transcriptional responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Distinct mechanisms of activation of Stat1 and Stat3 by platelet-derived growth factor receptor in a cell-free system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Structure of the amino-terminal protein interaction domain of STAT-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Regulation of matrix metalloproteinase expression in tumor invasion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Mechanism by which the IFN-beta enhanceosome activates transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Negative modulation of alpha1(I) procollagen gene expression in human skin fibroblasts: transcriptional inhibition by interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203525

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203525

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference