(Q33942341)

30 July 2017

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title

Pancreatic cancer: a review of emerging therapies (English)

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30 July 2017

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Rosenberg L

1

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30 July 2017

1 May 2000

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30 July 2017

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30 July 2017

59

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30 July 2017

1071-1089

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30 July 2017

5

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https://scigraph.springernature.com/pub.10.2165/00003495-200059050-00004

30 July 2017

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Treatment of pancreatic cancer: current limitations, future possibilities

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Up-regulation of somatostatin receptors by epidermal growth factor and gastrin in pancreatic cancer cells

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A phase I clinical, plasma, and cellular pharmacology study of gemcitabine

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Programmed cell death (apoptosis) in pancreatic cancers of hamsters after treatment with analogs of both luteinizing hormone-releasing hormone and somatostatin

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12 December 2020

A randomized controlled trial of adjuvant immunotherapy (murine monoclonal antibody 494/32) in resectable pancreatic cancer.

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12 December 2020

Distribution of extracellular matrix proteins in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro.

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12 December 2020

Enhancement of tamoxifen-induced suppression of insulin-like growth factor I gene expression and serum level by a somatostatin analogue

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[Immunotherapy of advanced pancreatic carcinoma with the monoclonal antibody BW 494]

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Immunotherapy with Monoclonal Antibody (Mab) in Pancreatic Adenocarcinoma

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Treatment of adenocarcinoma of the pancreas with somatostatin and gonadoliberin (luteinizing hormone-releasing hormone). The French Associations for Surgical Research

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Antitumor effects of analogs of LH-RH and somatostatin: experimental and clinical studies

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A controlled trial of combination chemotherapy with 5-FU and BCNU in pancreatic cancer

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Immunoscintigraphy and radioimmunotherapy in patients with pancreatic carcinoma.

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Cancer statistics, 1995.

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Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma.

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Tumors undergoing rejection induced by monoclonal antibodies of the IgG2a isotype contain increased numbers of macrophages activated for a distinctive form of antibody-dependent cytolysis

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The matrix metalloproteinases and their inhibitors in pancreatic cancer. From molecular science to a clinical application

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Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines.

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12 December 2020

Expression of the somatostatin receptor subtype-2 gene predicts response of human pancreatic cancer to octreotide

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12 December 2020

Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.

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12 December 2020

Arotinoid mofarotene (RO40-8757) up-regulates p21 and p27 during growth inhibition of pancreatic cancer cell lines

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12 December 2020

Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.

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12 December 2020

Treatment of advanced pancreatic carcinoma with the somatostatin analogue BIM 23014. Preliminary results of a pilot study

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12 December 2020

New developments in chemotherapy for patients with advanced pancreatic cancer

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12 December 2020

Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas

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12 December 2020

Effects of gastrointestinal hormones on pancreatic growth

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12 December 2020

Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides

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12 December 2020

Phase II trial of interferon gamma and monoclonal antibody 17-1A in pancreatic cancer: biologic and clinical effects

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12 December 2020

Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients

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12 December 2020

The spread and prognosis of carcinoma in the region of the pancreatic head

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12 December 2020

Development of experimental cancer in the head of the pancreas by surgical induction of tissue injury.

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12 December 2020

Potentiation of the anti-proliferative effects of anti-cancer drugs by octreotide in vitro and in vivo

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12 December 2020

Biology of pancreatic cancer

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12 December 2020

Regulation of matrix metalloproteinases - their role in tumor invasion and metastasis

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12 December 2020

Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype

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12 December 2020

Trimetrexate in locally advanced or metastatic adenocarcinoma of the pancreas. A phase II study of the Northern California Oncology Group.

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12 December 2020

A monoclonal antibody with binding and inhibiting activity towards human pancreatic carcinoma cells. I. Immunohistological and immunochemical characterization of a murine monoclonal antibody selecting for well differentiated adenocarcinomas of the p

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12 December 2020

Cigarette smoking and pancreas cancer: a case-control study based on direct interviews

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12 December 2020

Radiosensitization of pancreatic cancer cells by 2',2'-difluoro-2'-deoxycytidine

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12 December 2020

Treatment of patients with metastatic pancreatic and gastrointestinal tumours with the somatostatin analogue Sandostatin: a phase II study including endocrine effects

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12 December 2020

Phase II trial of fazarabine (arabinofuranosyl-5-azacytidine) in patients with advanced pancreatic adenocarcinoma

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12 December 2020

A phase II trial of recombinant human interferon-gamma and recombinant tumor necrosis factor in patients with advanced gastrointestinal malignancies: results of a trial terminated by excessive toxicity

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12 December 2020

[Therapy of pancreatic carcinoma with the monoclonal antibody BW 494/32: first clinical results]

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12 December 2020

Role of octreotide in the treatment of pancreatic cancer.

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12 December 2020

Effect of somatostatin and tamoxifen on the growth of human pancreatic cancers in nude mice

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12 December 2020

The somatostatin receptor in the GI tract

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12 December 2020

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12 December 2020

Effects of short-term subcutaneous administration of SMS 201-995 on calcitonin plasma levels in patients suffering from medullary thyroid carcinoma

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12 December 2020

Randomized study of 5-FU and CCNU in pancreatic cancer: report of the Veterans Administration Surgical Adjuvant Cancer Chemotherapy Study Group

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12 December 2020

Low dose octreotide and tamoxifen in the treatment of adenocarcinoma of the pancreas.

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12 December 2020

Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase

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12 December 2020

Phase II trial of edatrexate in patients with advanced pancreatic adenocarcinoma

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12 December 2020

Studies of pancreatic cancer utilizing monoclonal antibodies

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12 December 2020

A study of 9-nitrocamptothecin (RFS-2000) in patients with advanced pancreatic cancer

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12 December 2020

Somatostatin and somatostatin analogues in oncology

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12 December 2020

Survival benefit of tamoxifen therapy in adenocarcinoma of pancreas. A case-control study

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12 December 2020

Pancreatic adenocarcinoma: epidemiology and genetics

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12 December 2020

Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients

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12 December 2020

Pancreatic cancer: the greatest oncological challenge

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12 December 2020

Phase II study of amonafide in advanced pancreatic adenocarcinoma

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12 December 2020

The clinical significance of p21(WAF1/CIP-1) and p53 expression in pancreatic adenocarcinoma

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12 December 2020

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12 December 2020

Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms

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12 December 2020

The interrelationship between the anti-mitotic action of the somatostatin analog octreotide and that of cytostatic drugs and suramin

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12 December 2020

Oestrogen receptor proteins in malignant and fetal pancreas

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12 December 2020

Octreotide combined with goserelin in the therapy of advanced pancreatic cancer--results of a pilot study and review of the literature

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12 December 2020

Phase II trial of gemcitabine (2,2'-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas

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12 December 2020

Smoking and cancer with emphasis on Europe

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12 December 2020

The Role of Somatostatin and Its Analogs in the Diagnosis and Treatment of Tumors

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12 December 2020

Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine

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12 December 2020

Monoclonal antibody CO17-1A and leukapheresis in immunotherapy of pancreatic cancer.

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12 December 2020

The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins

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12 December 2020

Somatostatin analogues inhibit growth of pancreatic cancer by stimulating tyrosine phosphatase

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12 December 2020

Molecular biology of somatostatin receptors

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12 December 2020

Treatment of advanced pancreatic cancer with high-dose octreotide

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12 December 2020

Low-dose octreotide treatment is not effective in patients with advanced pancreatic cancer

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12 December 2020

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12 December 2020

Comparison of somatostatin and its highly potent hexa- and octapeptide analogs on exocrine and endocrine pancreatic secretion

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12 December 2020

Percolation and binding of monoclonal antibody BW494 to pancreatic carcinoma tissues during high dose immunotherapy and consequences for future therapy modalities

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12 December 2020

Cytotoxic analog of somatostatin containing methotrexate inhibits growth of MIA PaCa-2 human pancreatic cancer xenografts in nude mice

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12 December 2020

Trial of therapy with monoclonal antibody 17-1A in pancreatic carcinoma: preliminary results

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12 December 2020

Phase I trial of chimeric (human-mouse) monoclonal antibody L6 in patients with non-small-cell lung, colon, and breast cancer

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12 December 2020

A rationale for expanding the endpoints for clinical trials in advanced pancreatic carcinoma

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12 December 2020

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

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12 December 2020

Cancer of the pancreas. 50 years of surgery

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12 December 2020

Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4

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12 December 2020

Epidemiology of pancreatic cancer

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12 December 2020

Promoting effect of truncal vagotomy on pancreatic carcinogenesis initiated with N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters

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12 December 2020

Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).

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12 December 2020

Radioimmunotherapy of xenografts of human pancreatic carcinomas--intravenous and intratumoral application of 131I-labelled monoclonal antibodies.

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12 December 2020

A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin

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12 December 2020

The integration of chemotherapy into a combined modality approach for cancer treatment. VI. Pancreatic adenocarcinoma

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12 December 2020

Gemcitabine for pancreatic cancer: how hard to look for clinical benefit? An American perspective

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12 December 2020

Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1.

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12 December 2020

Monoclonal antibody-beta-lactamase conjugates for the activation of a cephalosporin mustard prodrug

1 reference

12 December 2020

Gastroenteropancreatic endocrine tumours: effect of Sandostatin on tumour growth. The German Sandostatin Study Group

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12 December 2020

Androgen receptor in human normal and malignant pancreatic tissue and cell lines

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12 December 2020

Pancreatic cancer: 1998 update

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12 December 2020

Membrane receptors for peptides in experimental and human pancreatic cancers

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12 December 2020

Angiogenesis and tumor metastasis

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12 December 2020

Clinical Trials Referral Resource. Trials using tumor vaccines

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12 December 2020

G207, modified herpes simplex virus type 1, kills human pancreatic cancer cells in vitro

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12 December 2020

Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer

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12 December 2020

Antiproliferative effects of somatostatin and the somatostatin analog SMS 201-995 on three human breast cancer cell lines

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12 December 2020

Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).

1 reference

12 December 2020

Potential role of somatostatin analogues in the treatment of cancer

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12 December 2020

Evaluation of combination chemotherapy and phase II agents in pancreatic adenocarcinoma. A Southwest Oncology Group study

1 reference

12 December 2020

AGA technical review on the epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. American Gastroenterological Association

1 reference

12 December 2020

Adenocarcinoma of the pancreas--a hormone sensitive tumor? A preliminary report on Nolvadex treatment

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12 December 2020

Gene therapy for colon cancer with the herpes simplex thymidine kinase gene

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12 December 2020

Steroid receptors in exocrine glands: The pancreas and prostate

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12 December 2020

A study of tobacco carcinogenesis: effect of the fat content of the diet on the carcinogenic activity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats

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12 December 2020

Establishment of a human pancreatic tumor xenograft model: potential application for preclinical evaluation of novel therapeutic agents

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12 December 2020

Distribution of type IV collagen in pancreatic adenocarcinoma and chronic pancreatitis

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12 December 2020

Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney

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12 December 2020

Novel approaches in development for the treatment of pancreatic cancer

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12 December 2020

Inhibitory effects of analogs of luteinizing hormone-releasing hormone and somatostatin on pancreatic cancers in hamsters. Events that accompany tumor regression

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12 December 2020

Effects of chronic administration of somatostatin on rat exocrine pancreas

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12 December 2020

Activation of Prodrugs by Antibody-Enzyme Conjugates

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12 December 2020

Sex-steroid enzymes, aromatase and 5 alpha-reductase in the pancreas: a comparison of normal adult, foetal and malignant tissue

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12 December 2020

Somatostatin analogue SMS 201-995 reduces serum IGF-I levels in patients with neoplasms potentially dependent on IGF-I.

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12 December 2020

Immunohistochemical detection of laminin in 98 human breast carcinomas: a light and electron microscopic study

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12 December 2020

Long-term treatment of a VIPoma with somatostatin analogue resulting in remission of symptoms and possible shrinkage of metastases

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12 December 2020

GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma

1 reference

12 December 2020

Role of epidermal growth factor in carcinogenesis.

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12 December 2020

A randomised trial of octreotide vs best supportive care only in advanced gastrointestinal cancer patients refractory to chemotherapy

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12 December 2020

Inhibition of growth of two human pancreatic adenocarcinomas in vivo by somatostatin analog SMS 201-995.

1 reference

12 December 2020

Activation of prodrugs by antibody-enzyme conjugates: a new approach to cancer therapy.

1 reference

12 December 2020

Cholecystokinin inhibits DNA alkylation induced by N-nitrosobis (2-oxopropyl)amine (BOP) in hamster pancreas

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12 December 2020

Phase II evaluation of iproplatin in patients with advanced gastric and pancreatic cancer

1 reference

12 December 2020

Phase I trial of recombinant human gamma-interferon and recombinant human tumor necrosis factor in patients with advanced gastrointestinal cancer

1 reference

12 December 2020

Tumor invasion and metastasis: an imbalance of positive and negative regulation.

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12 December 2020

Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.

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12 December 2020

Molecular aspects of the metastatic cascade

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12 December 2020

Treatment of nitrosamine-induced pancreatic tumors in hamsters with analogs of somatostatin and luteinizing hormone-releasing hormone

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12 December 2020

Docetaxel (Taxotere) in the treatment of solid tumors other than breast and lung cancer.

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12 December 2020

Chemotherapy in pancreatic cancer: results of a controlled, prospective, randomised, multicentre trial.

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12 December 2020

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

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12 December 2020

A clinicopathologic study on neural invasion in cancer of the pancreatic head

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12 December 2020

Purification and partial characterization of a 17 beta-estradiol-binding macromolecule in the human pancreas

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12 December 2020

The basement membrane in pathology.

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12 December 2020

The use of chemotherapy in the treatment of advanced gastric and pancreas cancer.

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12 December 2020

Collective review of small carcinomas of the pancreas

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12 December 2020

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

1 reference

12 December 2020

Effects of monoclonal antibody immunotherapy on patients with gastrointestinal adenocarcinoma

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12 December 2020

Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokines

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12 December 2020

Characterization of cloned human somatostatin receptor SSTR5.

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12 December 2020

Effect of the long-acting somatostatin analogue SMS 201-995 (Sandostatin) in advanced breast cancer

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12 December 2020

Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas

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12 December 2020

Nicotine-derived N-nitrosamines (TSNA) and their relevance in tobacco carcinogenesis

1 reference

12 December 2020

A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer

1 reference

12 December 2020

Phase II multicenter evaluation of prolonged murine monoclonal antibody 17-1A therapy in pancreatic carcinoma

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12 December 2020

10.2165/00003495-200059050-00004

Identifiers

DOI

1 reference

PubMed ID

10852640

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

10852640