(Q33972465)

30 July 2017

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title

The enantioselectivity of enzymes involved in current antiviral therapy using nucleoside analogues: a new strategy? (English)

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30 July 2017

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G Maury

1

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30 July 2017

publication date

1 May 2000

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Antiviral Chemistry & Chemotherapy

30 July 2017

published in

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30 July 2017

volume

11

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30 July 2017

issue

3

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30 July 2017

page(s)

165-189

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Homogeneous pyrimidine nucleotidase from human erythrocytes: enzymic and molecular properties

30 July 2017

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21 January 2018

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New approaches to the synthesis of antiviral nucleosides

21 January 2018

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

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Cloning and expression of human deoxyguanosine kinase cDNA

21 January 2018

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Enzymatic phosphorylation of the antiherpetic agent 9-[(2,3-dihydroxy-1-propoxy)methyl]guanine

21 January 2018

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Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution

21 January 2018

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Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

21 January 2018

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Unique inhibitory effect of 1-(2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl)-5-methyluracil 5'-triphosphate on Epstein-Barr virus and human DNA polymerases

21 January 2018

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Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A review

21 January 2018

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Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation

21 January 2018

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Expression of an enzymatically active polymerase of human hepatitis B virus in an coupled transcription-translation system

21 January 2018

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Synthesis and biological evaluation of 2',3'-dideoxy-L-pyrimidine nucleosides as potential antiviral agents against human immunodeficiency virus (HIV) and hepatitis B virus (HBV).

21 January 2018

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Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs

21 January 2018

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Kinetic studies with N2-phenylguanines and with L-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site

21 January 2018

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Lack of stereospecificity of suid pseudorabies virus thymidine kinase

21 January 2018

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The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro

21 January 2018

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Selectivity of DNA polymerases toward α and β nucleotide substrates of d and l series

21 January 2018

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21 January 2018

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21 January 2018

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L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth.

21 January 2018

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21 January 2018

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Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases

21 January 2018

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Chemo-enzymatic synthesis of a new type of enantiomerically pure carbocyclic nucleoside analogues with strong inhibitory effects on terminal deoxynucleotidyl transferase

21 January 2018

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21 January 2018

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Use of isotopically chiral [4'-13C]penciclovir and 13C NMR to determine the specificity and absolute configuration of penciclovir phosphate esters formed in HSV-1 and HSV-2 infected cells and by HSV-1-encoded thymidine kinase

21 January 2018

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Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues

21 January 2018

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Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100301

Cloning and expression of human mitochondrial deoxyguanosine kinase cDNA

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100301

The three-dimensional structure of thymidine kinase from herpes simplex virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100301

The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue

21 January 2018

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A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water

21 January 2018

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21 January 2018

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Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate

21 January 2018

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Cytidine deaminase complexed to 3-deazacytidine: a "valence buffer" in zinc enzyme catalysis

21 January 2018

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The structure of the cytidine deaminase-product complex provides evidence for efficient proton transfer and ground-state destabilization

21 January 2018

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Chiral discrimination of enantiomeric 2'-deoxythymidine 5'-triphosphate by HIV-1 reverse transcriptase and eukaryotic DNA polymerases

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100301

Inhibition of Epstein-Barr virus replication by a novel L-nucleoside, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100301

A comparison of the enantioselectivities of human deoxycytidine kinase and human cytidine deaminase∗

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100301

Inhibitory Effect of Penciclovir-Triphosphate on Duck Hepatitis B Virus Reverse Transcription

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100301

10.1177/095632020001100301

21 January 2018

Identifiers

DOI

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30 July 2017

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