(Q33978913)

30 July 2017

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution (English)

1 reference

30 July 2017

Michael R Wester

1

1 reference

30 July 2017

Jason K Yano

2

1 reference

30 July 2017

Guillaume A Schoch

3

1 reference

30 July 2017

Christine Yang

4

1 reference

30 July 2017

Keith J Griffin

5

1 reference

30 July 2017

C David Stout

6

1 reference

30 July 2017

Eric F Johnson

7

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30 July 2017

language of work or name

English

0 references

publication date

4 June 2004

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Journal of Biological Chemistry

30 July 2017

8

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based on heuristic

inferred from page(s)

published in

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30 July 2017

279

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30 July 2017

35630-35637

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30 July 2017

34

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Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.

30 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Cytochrome P450 epoxygenases as EDHF synthase(s).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Crystal structure of human cytochrome P450 2C9 with bound warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Identification of amino acid substitutions that confer a high affinity for sulfaphenazole binding and a high catalytic efficiency for warfarin metabolism to P450 2C19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Development of a combined protein and pharmacophore model for cytochrome P450 2C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Purification and crystallization of N-terminally truncated forms of microsomal cytochrome P450 2C5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Microsomal P450 2C3 is expressed as a soluble dimer in Escherichia coli following modification of its N-terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Role of conserved Asp293 of cytochrome P450 2C9 in substrate recognition and catalytic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

27 Measurement of substrate and inhibitor binding to microsomal cytochrome P-450 by optical-difference spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Thermodynamics of water mediating protein-ligand interactions in cytochrome P450cam: a molecular dynamics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

PRODRG, a program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Role of cytochrome P450 2C9 and an allelic variant in the 4'-hydroxylation of (R)- and (S)-flurbiprofen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Raster3D: photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

Detection, delineation, measurement and display of cavities in macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405427200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405427200

1 reference

30 July 2017

1 reference