(Q34005966)

30 July 2017

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors (English)

1 reference

30 July 2017

17

Gitte Neubauer

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Toby Mathieson

Toby Mathieson

7

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Yann Abraham

Yann Abraham

3

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Gerard Drewes

Gerard Drewes

21

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Carsten Hopf

Carsten Hopf

15

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Bernhard Kuster

Bernhard Kuster

20

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Marcus Bantscheff

1

Marcus Bantscheff

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30 July 2017

2

Dirk Eberhard

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30 July 2017

4

Sonja Bastuck

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30 July 2017

5

Markus Boesche

1 reference

30 July 2017

8

Jessica Perrin

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30 July 2017

9

Manfred Raida

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30 July 2017

11

Valérie Reader

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30 July 2017

12

Gavain Sweetman

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30 July 2017

14

Tewis Bouwmeester

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30 July 2017

16

Ulrich Kruse

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30 July 2017

18

Nigel Ramsden

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30 July 2017

19

Jens Rick

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30 July 2017

Scott Hobson

6

1 reference

PubMed ID

17721511

30 July 2017

Christina Rau

10

1 reference

PubMed ID

17721511

30 July 2017

Andreas Bauer

13

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30 July 2017

26 August 2007

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30 July 2017

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30 July 2017

25

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30 July 2017

1035-1044

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30 July 2017

9

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https://scigraph.springernature.com/pub.10.1038/nbt1328

30 July 2017

0 references

cites work

Chemoproteomics-driven drug discovery: addressing high attrition rates

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7 January 2021

From magic bullets to designed multiple ligands

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7 January 2021

Protein kinases--the major drug targets of the twenty-first century?

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7 January 2021

Rational design of inhibitors that bind to inactive kinase conformations

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7 January 2021

Strategies to overcome resistance to targeted protein kinase inhibitors

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7 January 2021

The protein kinase complement of the human genome

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7 January 2021

The purinome, a complex mix of drug and toxicity targets

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7 January 2021

A small molecule-kinase interaction map for clinical kinase inhibitors

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7 January 2021

Analysis of drug-induced effect patterns to link structure and side effects of medicines

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7 January 2021

Fishing for targets: novel approaches using small molecule baits

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7 January 2021

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

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7 January 2021

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

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7 January 2021

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

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7 January 2021

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

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7 January 2021

Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug

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7 January 2021

Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia

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7 January 2021

Synthetic small molecules that control stem cell fate

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7 January 2021

Large-scale proteomic analysis of the human spliceosome

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7 January 2021

Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors.

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7 January 2021

Discovery of novel targets of quinoline drugs in the human purine binding proteome

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7 January 2021

1 reference

7 January 2021

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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7 January 2021

Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases

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7 January 2021

Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases

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7 January 2021

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

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7 January 2021

Large-scale analysis of the human and mouse transcriptomes

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7 January 2021

Functional analysis of discoidin domain receptor 1: effect of adhesion on DDR1 phosphorylation

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7 January 2021

NRH:quinone reductase 2: an enzyme of surprises and mysteries

1 reference

7 January 2021

Functional interrogation of the kinome using nucleotide acyl phosphates

1 reference

7 January 2021

Features of selective kinase inhibitors

1 reference

7 January 2021

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

1 reference

7 January 2021

Some parameters relevant to affinity chromatography on immobilized nucleotides

1 reference

7 January 2021

Sensing extracellular matrix: an update on discoidin domain receptor function

1 reference

7 January 2021

p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop

1 reference

7 January 2021

Effect of STI-571 (imatinib mesylate) in combination with retinoic acid and gamma-irradiation on viability of neuroblastoma cells

1 reference

7 January 2021

Discoidin domain receptor 1-deficient mice are resistant to bleomycin-induced lung fibrosis

1 reference

7 January 2021

Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis

1 reference

7 January 2021

Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis

1 reference

7 January 2021

Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex

1 reference

7 January 2021

7-Alkoxy-4-phenylamino-3-quinolinecar-bonitriles as dual inhibitors of Src and Abl kinases

1 reference

7 January 2021

2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (d

1 reference

7 January 2021

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1 reference

7 January 2021

Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NBT1328

1 reference

30 July 2017

1 reference

PubMed ID

17721511