(Q34010366)

30 July 2017

title

Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study (English)

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30 July 2017

Shannon E Telesco

1

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30 July 2017

Ravi Radhakrishnan

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 March 2009

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30 July 2017

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30 July 2017

volume

96

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30 July 2017

issue

6

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30 July 2017

page(s)

2321-2334

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

30 July 2017

cites work

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HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

5 July 2018

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5 July 2018

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5 July 2018

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Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Structure of the extracellular region of HER3 reveals an interdomain tether

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

5 July 2018

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5 July 2018

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VMD: visual molecular dynamics

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907720

Ligand binding: molecular mechanics calculation of the streptavidin-biotin rupture force

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907720

Comparative protein modelling by satisfaction of spatial restraints

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907720

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907720

Mutational activation of ErbB2 reveals a new protein kinase autoinhibition mechanism

5 July 2018

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Absence of autophosphorylation site Y882 in the p185neu oncogene product correlates with a reduction of transforming potential

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907720

Detection of epidermal growth factor receptor and human epidermal growth factor receptor 2 activating mutations in lung adenocarcinoma by high-resolution melting amplicon analysis: correlation with gene copy number, protein expression, and hormone r

29 October 2018

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12 December 2020

Software news and updates. Carma: a molecular dynamics analysis program

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12 December 2020

Detection of EGFR- and HER2-activating mutations in squamous cell carcinoma involving the head and neck

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12 December 2020

Incorporating the effect of ionic strength in free energy calculations using explicit ions

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12 December 2020

Hidden thermodynamics of mutant proteins: a molecular dynamics analysis

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12 December 2020

10.1016/J.BPJ.2008.12.3912

Identifiers

DOI

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30 July 2017

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30 July 2017

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