(Q34024316)

30 July 2017

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title

Man-made enzymes--from design to in vitro compartmentalisation (English)

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30 July 2017

Griffiths AD

1

1 reference

PubMed ID

10975453

30 July 2017

Tawfik DS

series ordinal

2

1 reference

PubMed ID

10975453

30 July 2017

language of work or name

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1 August 2000

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Current Opinion in Biotechnology

30 July 2017

1 reference

30 July 2017

11

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30 July 2017

338-353

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30 July 2017

4

1 reference

Relation between structure and function of alpha/beta-proteins

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

On the origin of enzymatic species

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Evolution of protein function, from a structural perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Recombinant proteins for genetic disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Protein evolution by molecular breeding

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Directed evolution of biocatalysts

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Biotechnology in the 21st century

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

The design of linear peptides that fold as monomeric beta-sheet structures.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

On the failure of de novo-designed peptides as biocatalysts

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Catalytic promiscuity and the evolution of new enzymatic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Strategies for selection of antibodies by phage display

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Finding Cinderella's slipper--proteins that fit

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Mechanism of allergic cross-reactions—I. Multispecific binding of ligands to a mouse monoclonal anti-DNP IgE antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Probability model for molecular recognition in biological receptor repertoires: significance to the olfactory system

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Isolation of high affinity human antibodies directly from large synthetic repertoires.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Off-the-shelf proteins that rival tailor-made antibodies as catalysts.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

In vitro selection of functional nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Constructing high complexity synthetic libraries of long ORFs using in vitro selection

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A hierarchical approach to protein molecular evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

1 reference

7 January 2021

Recent advances in producing and selecting functional proteins by using cell-free translation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Totally in vitro protein selection using mRNA-protein fusions and ribosome display

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Screening of peptide libraries linked to lac repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

In vitro selection of nucleic acids and proteins: What are we learning?

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Selection for improved subtiligases by phage display

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A method for directed evolution and functional cloning of enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A method for the selection of catalytic activity using phage display and proximity coupling.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Man-made cell-like compartments for molecular evolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Polymerase chain reaction in liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

STABLE: protein-DNA fusion system for screening of combinatorial protein libraries in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Probing the importance of second sphere residues in an esterolytic antibody by phage display

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Phage display of a catalytic antibody to optimize affinity for transition-state analog binding

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Kinetic and affinity limits on antibodies produced during immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Transition-state stabilization as a measure of the efficiency of antibody catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

The potential of catalytic antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

catELISA: a facile general route to catalytic antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Chemical selection for catalysis in combinatorial antibody libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Broadening the Aldolase Catalytic Antibody Repertoire by Combining Reactive Immunization and Transition State Theory: New Enantio- and Diastereoselectivities

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Catalytic antibodies--reaching adolescence?

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

In vivo versus in vitro screening or selection for catalytic activity in enzymes and abzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A general purpose RNA-cleaving DNA enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A small catalytic RNA motif with Diels-Alderase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

RNA-catalysed carbon–carbon bond formation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Molecular evolution of an arsenate detoxification pathway by DNA shuffling.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

3D structural information as a guide to protein engineering using genetic selection

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Combinatorial protein design: strategies for screening protein libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Detection of catalytic monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Catalytic antibodies: perusing combinatorial libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

1 reference

7 January 2021

The X-ray Structure of a Transition State Analog Complex Reveals the Molecular Origins of the Catalytic Power and Substrate Specificity of Acetylcholinesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Can small cyclic peptides have the activity and specificity of proteolytic enzymes?

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Toward an efficient DNAzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Signal sequence-independent protein secretion in gram-negative bacteria: colicin V and microcin B17.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Reactive immunization

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Evolving catalytic antibodies in a phage-displayed combinatorial library

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Antibody-catalyzed porphyrin metallation.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A catalytic DNA for porphyrin metallation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

A general method for the spatially defined immobilization of biomolecules on glass surfaces using "caged" biotin

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900109-9

7 January 2021

10.1016/S0958-1669(00)00109-9

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10975453