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The importance of being K-Ras
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The importance of being K-Ras
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
author name string
Ellis CA
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
Clark G
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
publication date
1 July 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Cellular Signalling
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
volume
12
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
page(s)
425-434
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
issue
7
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
cites work
ras genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The GTPase superfamily: a conserved switch for diverse cell functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Function and regulation of ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmentally-regulated expression of murine K-ras isoforms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TC21 and Ras share indistinguishable transforming and differentiating activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increasing complexity of Ras signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction from multiple Ras effectors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian Ras interacts directly with the serine/threonine kinase Raf
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of phosphoinositide-3-OH kinase in Ras signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ralGDS family members interact with the effector loop of ras p21.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a Ras/Ral signaling cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Ce-AF-6, a novel Caenorhabditis elegans protein, as a putative Ras effector.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Nore1 as a potential Ras effector
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-GTPase activating protein (GAP): a putative effector for Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras--a versatile cellular switch
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increasing complexity of the Ras signaling pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of mammary cancer and lymphoma by multiple, low oral doses of 7,12-dimethylbenz[a]anthracene in SENCAR mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of ras mutations in liver neoplasms from B6C3F1 mice exposed to tetrafluoroethylene for two years.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of ras oncogenes in chemically transformed BALB/MK-2 mouse keratinocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
H- and K-ras mutational profiles in chemically induced liver tumors from B6C3F1 and CD-1 mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid modifications and function of the ras superfamily of proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein prenylation: more than just glue?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Palmitoylation of Ha-Ras facilitates membrane binding, activation of downstream effectors, and meiotic maturation in Xenopus oocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dynamic role of palmitoylation in signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polylysine domain of K-ras 4B protein is crucial for malignant transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of rasGAP and neurofibromatosis gene product activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of RasGRP via a phorbol ester-responsive C1 domain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: multiple interference with the isoprenoid pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-beta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transient palmitoylation supports H-Ras membrane binding but only partial biological activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive autoregulation of ras genes expression in fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription of unr (upstream of N-ras) down-modulates N-ras expression in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estrogen inducibility of c-Ha-ras transcription in breast cancer cells. Identification of functional estrogen-responsive transcriptional regulatory elements in exon 1/intron 1 of the c-Ha-ras gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 3Rs of life: Ras, Raf and growth regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The complexity of Raf-1 regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct Raf domains mediate interaction with Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane recruitment of Raf-1 is not the only function of Ras in Raf-1 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MAP kinase cascade. Discovery of a new signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signalling through phosphoinositide 3-kinases: the lipids take centre stage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
When is a lipid kinase not a lipid kinase? When it is a protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms and consequences of activation of protein kinase B/Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-dependent activation of the small GTPase Ral.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of gene induction and cell growth by the Ras effector Rlf
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family members: activators of MAP kinase cascades.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional association between Arf and RalA in active phospholipase D complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of Ral GTPase in v-Src-induced phospholipase D activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eph receptors and ephrins restrict cell intermingling and communication.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of MEKK by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Mapping pathways for mitogen-activated protein kinase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-dependent growth factor regulation of MEK kinase in PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific interactions of Mss4 with members of the Rab GTPase subfamily.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mss4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p120 GAP modulates Ras activation of Jun kinases and transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Rho in Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between GTPase activators for Rho and Ras families.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid products of phosphoinositide 3-kinase interact with Rac1 GTPase and stimulate GDP dissociation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic c-Ki-ras but not oncogenic c-Ha-ras up-regulates CEA expression and disrupts basolateral polarity in colon epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Raf as a result of recruitment to the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical association with ras enhances activation of membrane-bound raf (RafCAAX).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RAF family: an expanding network of post-translational controls and protein-protein interactions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K-ras is an essential gene in the mouse with partial functional overlap with N-ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K-ras is essential for the development of the mouse embryo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional rafts in cell membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caveolin, cholesterol and Ras signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple Ras functions can contribute to mammalian cell transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900084-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0898-6568(00)00084-X
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
PubMed ID
10989276
1 reference
stated in
Europe PubMed Central
PubMed ID
10989276
retrieved
30 July 2017
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