(Q34037900)

30 July 2017

title

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity (English)

1 reference

30 July 2017

author

Christopher J. Schofield

17

1 reference

30 July 2017

Louise Walport

7

0 references

Yukihiro Itoh

object named as

Yukihiro Itoh

3

0 references

Akane Kawamura

object named as

Akane Kawamura

9

0 references

author name string

Takayoshi Suzuki

1

1 reference

30 July 2017

Hiroki Ozasa

2

1 reference

30 July 2017

Peng Zhan

4

1 reference

30 July 2017

Hideyuki Sawada

5

1 reference

30 July 2017

Koshiki Mino

6

1 reference

30 July 2017

Rei Ohkubo

8

1 reference

30 July 2017

Masato Yonezawa

10

1 reference

30 July 2017

Yuichi Tsukada

11

1 reference

30 July 2017

Anthony Tumber

12

1 reference

30 July 2017

Hidehiko Nakagawa

13

1 reference

30 July 2017

Makoto Hasegawa

14

1 reference

30 July 2017

Ryuzo Sasaki

15

1 reference

30 July 2017

Tamio Mizukami

16

1 reference

30 July 2017

Naoki Miyata

18

1 reference

30 July 2017

language of work or name

English

0 references

publication date

5 September 2013

1 reference

Journal of Medicinal Chemistry

30 July 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

30 July 2017

volume

56

1 reference

30 July 2017

issue

18

1 reference

30 July 2017

page(s)

7222-7231

1 reference

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Epigenetic protein families: a new frontier for drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Lysine demethylases inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

The Polycomb complex PRC2 and its mark in life

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

The Language of Histone Crosstalk

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Histone lysine demethylases: emerging roles in development, physiology and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

The role of chromatin during transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

JmjC-domain-containing proteins and histone demethylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

A crack in histone lysine methylation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Chemical genetics: where genetics and pharmacology meet

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929130

DNA methylation in rat liver by daminozide, 1,1-dimethylhydrazine, and dimethylnitrosamine

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23964788

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/23964788

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM400624B

1 reference

30 July 2017

1 reference

30 July 2017

1 reference