(Q34047220)

30 July 2017

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title

Inhibition of the type I insulin-like growth factor receptor expression and signaling: novel strategies for antimetastatic therapy (English)

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30 July 2017

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Brodt P

1

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30 July 2017

Samani A

series ordinal

2

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30 July 2017

Navab R

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

Biochemical Pharmacology

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30 July 2017

60

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30 July 2017

1101-1107

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30 July 2017

8

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30 July 2017

Cancer statistics, 1994.

1 reference

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The biology of cancer metastasis and implications for therapy

7 January 2021

1 reference

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Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

7 January 2021

1 reference

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G1 events and regulation of cell proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Growth factor receptor tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Protein modules and signalling networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

NIH conference. Insulin-like growth factors in health and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factors and their binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Role of insulin-like growth factor binding proteins in controlling IGF actions

7 January 2021

1 reference

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

7 January 2021

1 reference

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Insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the platelet-derived growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

The insulin signalling system and the IRS proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Mechanism of STAT3 activation by insulin-like growth factor I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factor I stimulates tyrosine phosphorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidylinositol 3'-kinase and formation of a p130(Cas).Crk complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Effect of mutations at serines 1280-1283 on the mitogenic and transforming activities of the insulin-like growth factor I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factors and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Controlling IGF-receptor function: a possible strategy for tumor therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

The IGF-I receptor in cancer research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Enhanced invasion and liver colonization by lung carcinoma cells overexpressing the type 1 insulin-like growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Mutant IGF-I receptors as dominant negatives for growth and transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Uptake of insulin and other ligands into receptor-rich endocytic components of target cells: the endosomal apparatus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Insulin-like growth factor-I receptor internalization regulates signaling via the Shc/mitogen-activated protein kinase pathway, but not the insulin receptor substrate-1 pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Comparison of the intracellular itineraries of insulin-like growth factor-I and insulin and their receptors in Rat-1 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Receptor-mediated endocytosis and lysosomal processing of insulin-like growth factor I by mitogenically responsive cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

Negative regulation of epidermal growth factor signaling by selective proteolytic mechanisms in the endosome mediated by cathepsin B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900422-6

10.1016/S0006-2952(00)00422-6

7 January 2021

Identifiers

DOI

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30 July 2017

1 reference