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The human LINE-1 retrotransposon creates DNA double-strand breaks.
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Europe PubMed Central
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4136747
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17 January 2020
title
The human LINE-1 retrotransposon creates DNA double-strand breaks
(English)
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stated in
Europe PubMed Central
PMCID
4136747
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
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17 January 2020
main subject
retrotransposon
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author
Prescott Deininger
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4
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Europe PubMed Central
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4136747
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
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17 January 2020
author name string
Stephen L Gasior
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1
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Europe PubMed Central
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4136747
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
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17 January 2020
Timothy P Wakeman
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2
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4136747
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
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17 January 2020
Bo Xu
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3
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4136747
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17 January 2020
language of work or name
English
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publication date
9 February 2006
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17 January 2020
published in
Journal of Molecular Biology
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4136747
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17 January 2020
volume
357
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Europe PubMed Central
PMCID
4136747
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17 January 2020
page(s)
1383-1393
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17 January 2020
issue
5
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4136747
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17 January 2020
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5 July 2018
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
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5 July 2018
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5 July 2018
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5 July 2018
Megabase chromatin domains involved in DNA double-strand breaks in vivo
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5 July 2018
Alu repeats and human disease
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5 July 2018
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5 July 2018
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5 July 2018
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
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5 July 2018
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5 July 2018
High frequency retrotransposition in cultured mammalian cells
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5 July 2018
Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
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High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia
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p53 is required for radiation-induced apoptosis in mouse thymocytes
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5 July 2018
Developmental and cell type specificity of LINE-1 expression in mouse testis: implications for transposition
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5 July 2018
Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis
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5 July 2018
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition
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5 July 2018
RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element
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5 July 2018
Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements
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5 July 2018
Heterochromatic recombination in germ cells of Drosophila melanogaster females.
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5 July 2018
Repair processes in radiation biology.
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5 July 2018
A simple technique for quantitation of low levels of DNA damage in individual cells
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5 July 2018
Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.
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5 July 2018
Transposable elements controlling I-R hybrid dysgenesis in D. melanogaster are similar to mammalian LINEs.
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retrieved
5 July 2018
Reverse Transcriptase Encoded by a Human Transposable Element
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
5 July 2018
Evidence for retrotransposition of the I factor, a LINE element of Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
5 July 2018
Active LINE-1 retrotransposons in human testicular cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
5 July 2018
Alu-linked hairpins efficiently mediate RNA interference with less toxicity than do H1-expressed short hairpin RNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Analyzing cell cycle checkpoints after ionizing radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
A potential role for the nucleolus in L1 retrotransposition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Retrotransposition of the Ll.LtrB group II intron proceeds predominantly via reverse splicing into DNA targets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
A transient assay reveals that cultured human cells can accommodate multiple LINE-1 retrotransposition events.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Thymocyte apoptosis induced by p53-dependent and independent pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136747
retrieved
28 October 2018
Genomic deletions created upon LINE-1 retrotransposition
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16490214
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Erratum: Retrotransposition of a bacterial group II intron
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16490214
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Group II intron mobility occurs by target DNA-primed reverse transcription
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16490214
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16490214
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IR hybrid dysgenesis increases the frequency of recombination in Drosophila melanogaster
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16490214
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JMB.2006.01.089
1 reference
stated in
Europe PubMed Central
PMCID
4136747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PMCID
4136747
1 reference
stated in
Europe PubMed Central
PMCID
4136747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed ID
16490214
1 reference
stated in
Europe PubMed Central
PMCID
4136747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16490214%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
7287431
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