(Q34070084)

30 July 2017

1 reference

title

New functions from old scaffolds: how nature reengineers enzymes for new functions (English)

1 reference

30 July 2017

1

Babbitt PC

1 reference

30 July 2017

Gerlt JA

2

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30 July 2017

1 January 2000

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Advances in Protein Chemistry

30 July 2017

1 reference

30 July 2017

55

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30 July 2017

1-28

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the alpha-protons of carboxylic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

The ENZYME data bank in 1999

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Insights into the mechanism of catalysis by the P-C bond-cleaving enzyme phosphonoacetaldehyde hydrolase derived from gene sequence analysis and mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

All in the family: structural and evolutionary relationships among three modular proteins with diverse functions and variable assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Fosfomycin resistance protein (FosA) is a manganese metalloglutathione transferase related to glyoxalase I and the extradiol dioxygenases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Elucidation of a monovalent cation dependence and characterization of the divalent cation binding site of the fosfomycin resistance protein (FosA).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Evolutionary relationships among extradiol dioxygenases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Evolution of the structure and chromosomal distribution of histidine biosynthetic genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

The evolution of alpha/beta barrel enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

A structural census of genomes: comparing bacterial, eukaryotic, and archaeal genomes in terms of protein structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Evolution of enzymatic activities in the enolase superfamily: crystal structure of (D)-glucarate dehydratase from Pseudomonas putida

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp. YL. An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

An evolutionary treasure: unification of a broad set of amidohydrolases related to urease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Structure-based identification of a novel NTPase from Methanococcus jannaschii

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

The metabolism of D-glucarate by Pseudomonas acidovorans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Hidden Markov models for detecting remote protein homologies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approach to database search

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mechanism of the reaction catalyzed by mandelate racemase. 3. Asymmetry in reactions catalyzed by the H297N mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

A carboxylate oxygen of the substrate bridges the magnesium ions at the active site of enolase: structure of the yeast enzyme complexed with the equilibrium mixture of 2-phosphoglycerate and phosphoenolpyruvate at 1.8 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mechanistic imperative for the evolution of a metalloglutathione transferase of the vicinal oxygen chelate superfamily.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Crystal structure of enolase indicates that enolase and pyruvate kinase evolved from a common ancestor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

The recognition of protein structure and function from sequence: adding value to genome data

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Catalytic promiscuity and the evolution of new enzymatic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Unexpected divergence of enzyme function and sequence: "N-acylamino acid racemase" is o-succinylbenzoate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Shotgun: getting more from sequence similarity searches

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mechanism of the reaction catalyzed by mandelate racemase. 1. Chemical and kinetic evidence for a two-base mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Toward identification of acid/base catalysts in the active site of enolase: comparison of the properties of K345A, E168Q, and E211Q variants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Structural and mechanistic studies of enolase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Three-dimensional structure of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 complexed with the substrate-analogue formate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

100,000 protein structures for the biologist

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Purification and properties of thermostable N-acylamino acid racemase from Amycolatopsis sp. TS-1-60

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Octahedral coordination at the high-affinity metal site in enolase: crystallographic analysis of the MgII--enzyme complex from yeast at 1.9 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Evidence that pcpA encodes 2,6-dichlorohydroquinone dioxygenase, the ring cleavage enzyme required for pentachlorophenol degradation in Sphingomonas chlorophenolica strain ATCC 39723.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

Mechanism of enolase: the crystal structure of enolase-Mg2(+)-2-phosphoglycerate/phosphoenolpyruvate complex at 2.2-A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955001-9

7 January 2021

10.1016/S0065-3233(01)55001-9

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11050931