(Q34071063)

25086775

30 July 2017

title

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages (English)

1 reference

30 July 2017

1 reference

2

1 reference

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1 June 2020

Joseph F. Urban

14

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1 June 2020

15

Maxim N Artyomov

1 reference

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1 June 2020

16

Erika L Pearce

1 reference

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1 June 2020

17

Edward J Pearce

1 reference

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1 June 2020

author name string

Stanley Ching-Cheng Huang

1

1 reference

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1 June 2020

Yulia Ivanova

3

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1 June 2020

David O'Sullivan

4

1 reference

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1 June 2020

Marcia Nascimento

5

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1 June 2020

Amber M Smith

6

1 reference

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1 June 2020

Wandy Beatty

7

1 reference

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1 June 2020

Latisha Love-Gregory

8

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1 June 2020

Wing Y Lam

9

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1 June 2020

Christina M O'Neill

10

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1 June 2020

Cong Yan

11

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1 June 2020

Hong Du

12

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1 June 2020

Nada A Abumrad

13

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1 June 2020

language of work or name

English

0 references

publication date

3 August 2014

1 reference

30 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086775%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

15

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1 June 2020

issue

9

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1 June 2020

page(s)

846-855

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086775%20AND%20SRC:MED&resulttype=core&format=json

Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

1 June 2020

cites work

1 reference

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Obesity activates a program of lysosomal-dependent lipid metabolism in adipose tissue macrophages independently of classic activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

28 July 2018

1 reference

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Single nucleotide polymorphisms within LIPA (Lysosomal Acid Lipase A) gene are associated with susceptibility to premature coronary artery disease. a replication in the genetic of atherosclerotic disease (GEA) Mexican study.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Oxidized LDL induces alternative macrophage phenotype through activation of CD36 and PAFR.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes.

28 July 2018

1 reference

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Macrophage biology in development, homeostasis and disease

28 July 2018

1 reference

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Metabolism of inflammation limited by AMPK and pseudo-starvation

28 July 2018

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Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

28 July 2018

1 reference

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Myocardial triacylglycerol metabolism.

28 July 2018

1 reference

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Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

28 July 2018

1 reference

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Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Bioenergetic profile experiment using C2C12 myoblast cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Alternative Macrophage Activation and Metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

28 July 2018

1 reference

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Development of monocytes, macrophages, and dendritic cells

28 July 2018

1 reference

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Autophagy regulates lipid metabolism

28 July 2018

1 reference

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Cellular fatty acid uptake: a pathway under construction

28 July 2018

1 reference

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Animal model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus.

28 July 2018

1 reference

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Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice.

28 July 2018

1 reference

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Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites

28 July 2018

1 reference

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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Alternative activation of macrophages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma

28 July 2018

1 reference

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Orlistat, a new lipase inhibitor for the management of obesity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Transcriptional regulation of lysosomal acid lipase in differentiating monocytes is mediated by transcription factors Sp1 and AP-2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Characterization of lysosomal acid lipase by site-directed mutagenesis and heterologous expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Labeling of adipocyte membranes by sulfo-N-succinimidyl derivatives of long-chain fatty acids: Inhibition of fatty acid transport

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths.

28 July 2018

1 reference

Metabolism in T cell activation and differentiation

21 January 2018

1 reference

The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics.

21 January 2018

1 reference

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

21 January 2018

1 reference

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 January 2018

1 reference

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

21 January 2018

1 reference

Long-term metabolic, endocrine, and neuropsychological outcome of hematopoietic cell transplantation for Wolman disease

21 January 2018

1 reference

Control of macrophage activation and function by PPARs

21 January 2018

1 reference

Interleukin-4 regulates lipid metabolism by inhibiting adipogenesis and promoting lipolysis

21 January 2018

1 reference

Low density receptor-related protein 1 (LRP1) promotes anti-inflammatory phenotype in murine macrophages

21 January 2018

1 reference

Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.

21 January 2018

1 reference

Mantle skewness and ridge segmentation

21 January 2018

1 reference

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

21 January 2018

1 reference

Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4139419

The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase

28 October 2018

1 reference

12 December 2020

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

1 reference

12 December 2020

Memory CD8 T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

1 reference

12 December 2020

Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.2956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086775%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086775%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25086775

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086775%20AND%20SRC:MED&resulttype=core&format=json