(Q34084707)

30 July 2017

Oncogenic transformation induced by membrane-targeted Akt2 and Akt3. (English)

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30 July 2017

M Aoki

5

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author name string

I Mende

1

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30 July 2017

S Malstrom

2

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30 July 2017

P N Tsichlis

3

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30 July 2017

P K Vogt

4

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30 July 2017

language of work or name

English

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publication date

1 July 2001

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30 July 2017

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30 July 2017

20

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30 July 2017

4419-4423

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30 July 2017

32

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204486

30 July 2017

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Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

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Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin

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The akt kinase: molecular determinants of oncogenicity

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The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity

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Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes

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AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

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7 January 2021

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

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7 January 2021

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

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7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

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7 January 2021

Cellular survival: a play in three Akts

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The multiple roles of PTEN in tumor suppression

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Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

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Phosphoinositide kinases

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Phosphatidylinositol kinase activity associates with viral p60src protein

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Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

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Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors

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Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

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7 January 2021

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

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7 January 2021

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3

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7 January 2021

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

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Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer

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7 January 2021

Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site.

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7 January 2021

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

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7 January 2021

Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

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7 January 2021

Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas

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7 January 2021

PIK3CA is implicated as an oncogene in ovarian cancer.

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7 January 2021

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

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7 January 2021

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

1 reference

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7 January 2021

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

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7 January 2021

Structure and function of phosphoinositide 3-kinases.

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204486

1 reference

Dimensions Publication ID

30 July 2017

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1 reference