(Q34093501)

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A decade of CDK5.

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scholarly article

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

A decade of CDK5. (English)

1 reference

Europe PubMed Central

31 July 2017

author name string

R Dhavan

1

1 reference

Europe PubMed Central

31 July 2017

L H Tsai

2

1 reference

Europe PubMed Central

31 July 2017

publication date

1 October 2001

1 reference

Europe PubMed Central

31 July 2017

Nature Reviews Molecular Cell Biology

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Europe PubMed Central

31 July 2017

2

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Europe PubMed Central

31 July 2017

749-759

1 reference

Europe PubMed Central

31 July 2017

10

1 reference

Europe PubMed Central

31 July 2017

https://scigraph.springernature.com/pub.10.1038/35096019

0 references

Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Expression of CDK5 (PSSALRE kinase), a neural cdc2-related protein kinase, in the mature and developing mouse central and peripheral nervous systems

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A brain-specific activator of cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The Xenopus laevis homologue to the neuronal cyclin-dependent kinase (cdk5) is expressed in embryos by gastrulation

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Neuronal differentiation and patterning in Xenopus: the role of cdk5 and a novel activator xp35.2.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cloning and characterization of the Drosophila melanogaster CDK5 homolog

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A novel yeast protein showing specific association with the cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Substrates for p34cdc2: in vivo veritas?

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The crystal structure of cyclin A

2 references

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Structural basis of cyclin-dependent kinase activation by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Identification of functional domains in the neuronal Cdk5 activator protein

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Changes in the expression of novel Cdk5 activator messenger RNA (p39nck5ai mRNA) during rat brain development.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Immunohistochemical localization of CDK5 activator p39 in the rat brain

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The expression of Cdk5, p35, p39, and Cdk5 kinase activity in developing, adult, and aged rat brains.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Synaptic localization of p39, a neuronal activator of cdk5

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Reconstitution of neuronal Cdc2-like kinase from bacteria-expressed Cdk5 and an active fragment of the brain-specific activator. Kinase activation in the absence of Cdk5 phosphorylation.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Interaction of cyclin-dependent kinase 5 (Cdk5) and neuronal Cdk5 activator in bovine brain.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A novel disruption of cortical development in p35(-/-) mice distinct from reeler.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Callosal axon guidance defects in p35(-/-) mice

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Role of cyclins in neuronal differentiation of immortalized hippocampal cells

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Rho GTPases in neuronal morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Interaction of neuronal Cdc2-like protein kinase with microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assembly

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Microtubule-stimulated phosphorylation of tau at Ser202 and Thr205 by cdk5 decreases its microtubule nucleation activity.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Morphogenetic roles of classic cadherins

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cadherins: a molecular family important in selective cell-cell adhesion

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

LIS1. let's interact sometimes... (part 1).

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Sec1/Munc18 proteins: mediators of membrane fusion moving to center stage

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. I. Identification of the kinase and its role in the turnoff of phosphodiesterase in vitro

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Expression of the neuronal cyclin-dependent kinase 5 activator p35Nck5a in human monocytic cells is associated with differentiation

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cyclin-dependent kinase 5 is associated with apoptotic cell death during development and tissue remodeling

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cyclin-dependent kinase 5 is expressed in both Sertoli cells and metaphase spermatocytes

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cyclin-dependent kinase 5 promotes insulin exocytosis.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Signaling phosphate starvation

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The cyclin family of budding yeast: abundant use of a good idea

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Interaction of yeast Rvs167 and Pho85 cyclin-dependent kinase complexes may link the cell cycle to the actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cak1 is required for Kin28 phosphorylation and activation in vivo.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

Phosphorylation of protein phosphatase inhibitor-1 by Cdk5

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

1 reference

https://api.crossref.org/works/10.1038%2F35096019

21 January 2018

A family of human cdc2-related protein kinases

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Mouse cyclin-dependent kinase (Cdk) 5 is a functional homologue of a yeast Cdk, pho85 kinase

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin alpha(1) beta(1)-mediated activation of cyclin-dependent kinase 5 activity is involved in neurite outgrowth and human neurofilament protein H Lys-Ser-Pro tail domain phosphorylation.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of cyclin-dependent kinase 5 in the hippocampus by chronic electroconvulsive seizures: role of [Delta]FosB.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine thymus

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal cyclin-dependent kinase 5 activity is critical for survival.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynamic behavior and organization of cytoskeletal proteins in neurons: reconciling old and new findings

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Cadherin-mediated cell-cell adhesion and neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Synapsin I, an actin-binding protein regulating synaptic vesicle traffic in the nerve terminal.

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Cdk5/p25(nck5a) interaction with synaptic proteins in bovine brain

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuron-specific Cdk5 kinase is responsible for mitosis-independent phosphorylation of c-Src at Ser75 in human Y79 retinoblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. II. Its role in the turnoff of phosphodiesterase in vivo

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Functions of Pho85 cyclin-dependent kinases in budding yeast

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

The Pho85 kinase, a member of the yeast cyclin-dependent kinase (Cdk) family, has a regulation mechanism different from Cdks functioning throughout the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2F35096019

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/35096019

1 reference

Europe PubMed Central

31 July 2017

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1 reference

Europe PubMed Central

31 July 2017

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