(Q34099588)

31 July 2017

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title

Clearing the brain's amyloid cobwebs (English)

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31 July 2017

Selkoe DJ

1

1 reference

PubMed ID

11683988

31 July 2017

language of work or name

English

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publication date

1 October 2001

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31 July 2017

1 reference

31 July 2017

32

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31 July 2017

177-180

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31 July 2017

2

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Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40).

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Degradation of amylin by insulin-degrading enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Neutral endopeptidase can hydrolyze beta-amyloid(1-40) but shows no effect on beta-amyloid precursor protein metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Metabolic regulation of brain Abeta by neprilysin.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Degradation of Alzheimer's beta-amyloid protein by human cathepsin D.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

New frontiers in Alzheimer's disease genetics

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

The plasmin system is induced by and degrades amyloid-beta aggregates

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900475-5

7 January 2021

10.1016/S0896-6273(01)00475-5

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11683988