(Q34100924)

31 July 2017

title

The genetic architecture of quantitative traits (English)

1 reference

31 July 2017

The Genetic Architecture of Quantitative Traits (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

26 January 2025

1 reference

heritable quantitative trait

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11700286

26 January 2025

author name string

T. F. Mackay

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11700286

26 January 2025

publication date

1 January 2001

1 reference

31 July 2017

2001

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11700286

26 January 2025

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11700286

https://www.annualreviews.org/doi/pdf/10.1146/annurev.genet.35.102401.090633

26 January 2025

work available at URL

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Annual Review of Genetics

26 January 2025

published in

1 reference

31 July 2017

volume

35

1 reference

31 July 2017

page(s)

303-339

1 reference

publication type of scholarly work

31 July 2017

review article

1 reference

Initial sequencing and analysis of the human genome

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The genetic architecture of odor-guided behavior in Drosophila melanogaster

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ON THE MEASUREMENT OF NATURAL AND SEXUAL SELECTION: THEORY

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Quantitative Trait Loci Affecting Differences in Floral Morphology Between Two Species of Monkeyflower (Mimulus)

26 January 2025

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Quantitative Trait Loci Affecting Body Weight and Fatness From a Mouse Line Selected for Extreme High Growth

26 January 2025

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Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

26 January 2025

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Association study designs for complex diseases

26 January 2025

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Quantitative trait locus for reading disability on chromosome 6

26 January 2025

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Use of in vitro mutagenesis to analyze the molecular basis of the difference in Adh expression associated with the allozyme polymorphism in Drosophila melanogaster

26 January 2025

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Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase

26 January 2025

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A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

26 January 2025

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Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

26 January 2025

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Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

26 January 2025

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Interval-specific congenic strains (ISCS): an experimental design for mapping a QTL into a 1-centimorgan interval

26 January 2025

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Experimental strategies for the genetic dissection of complex traits in animal models

26 January 2025

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A genome-wide search for human type 1 diabetes susceptibility genes

26 January 2025

41

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Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

26 January 2025

42

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Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).

26 January 2025

43

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The evolution of apical dominance in maize

26 January 2025

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The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes

26 January 2025

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Molecular-marker-facilitated investigations of quantitative trait loci in maize : 4. Analysis based on genome saturation with isozyme and restriction fragment length polymorphism markers

26 January 2025

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Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

26 January 2025

54

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Epistatic Interactions Between smell-impaired Loci in Drosophila melanogaster

26 January 2025

58

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

A simple genetic basis for a complex psychological trait in laboratory mice

26 January 2025

59

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Sex and Selection for a Quantitative Character in Drosophila II. The Sex Dimorphism

26 January 2025

60

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The effects of population size and selection intensity in selection for a quantitative character inDrosophila: III. Analyses of the lines

26 January 2025

63

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Forging links between population and quantitative genetics

26 January 2025

64

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fw2.2: a quantitative trait locus key to the evolution of tomato fruit size

26 January 2025

65

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

26 January 2025

66

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A recombination hotspot delimits a wild-species quantitative trait locus for tomato sugar content to 484 bp within an invertase gene.

26 January 2025

67

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QTL mapping of genotype–environment interaction for fitness in Drosophila melanogaster

26 January 2025

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26 January 2025

Life with 6000 genes

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Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

26 January 2025

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26 January 2025

The flexible genome

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Genotype-Environment Interaction at Quantitative Trait Loci Affecting Sensory Bristle Number in Drosophila melanogaster

26 January 2025

78

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

A simple regression method for mapping quantitative trait loci in line crosses using flanking markers

26 January 2025

80

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A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

26 January 2025

81

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Enzyme Polymorphisms in Man

26 January 2025

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The investigation of linkage between a quantitative trait and a marker locus

26 January 2025

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The diastrophic dysplasia gene encodes a novel sulfate transporter: positional cloning by fine-structure linkage disequilibrium mapping

26 January 2025

85

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Linkage disequilibrium in finite populations

26 January 2025

88

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Variances and covariances of squared linkage disequilibria in finite populations

26 January 2025

89

1 reference

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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

26 January 2025

91

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Comparing evolvability and variability of quantitative traits

26 January 2025

92

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Estimating the recombination parameter of a finite population model without selection

26 January 2025

94

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Multiple trait analysis of genetic mapping for quantitative trait loci

26 January 2025

98

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Variation for metrical characters in Drosophila populations. II. Natural selection

26 January 2025

100

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

The genetic architecture of body weight and egg hatchability in Drosophila melanogaster

26 January 2025

101

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Detection of quantitative trait loci from frequency changes of marker alleles under selection

26 January 2025

102

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A chromosomal analysis of egg production and abdominal chaeta number in Drosophila melanogaster

26 January 2025

107

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The Strength of Phenotypic Selection in Natural Populations

26 January 2025

109

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Mapping quantitative trait loci using molecular marker linkage maps

26 January 2025

110

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A cholesterol-lowering gene maps to chromosome 13q.

26 January 2025

111

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Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation

26 January 2025

114

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Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster

26 January 2025

115

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High-throughput methods for detection of genetic variation

26 January 2025

116

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Prospects for whole-genome linkage disequilibrium mapping of common disease genes

26 January 2025

117

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THE MEASUREMENT OF SELECTION ON CORRELATED CHARACTERS.

26 January 2025

119

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Restriction map variation in the Adh region of Drosophila

26 January 2025

121

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Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Drosophila melanogaster

26 January 2025

122

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quemao, a Drosophila Bristle Locus, Encodes Geranylgeranyl Pyrophosphate Synthase

26 January 2025

123

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Associations between DNA sequence variation and variation in expression of the Adh gene in natural populations of Drosophila melanogaster

26 January 2025

126

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An Introgression Analysis of Quantitative Trait Loci That Contribute to a Morphological Difference Between <i>Drosophila simulans</i> and <i>D. mauritiana</i>

26 January 2025

128

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Variation at the 87A heat shock locus in Drosophila melanogaster

26 January 2025

129

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A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura

26 January 2025

132

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Variation for metrical characters in Drosophila populations III. The nature of selection

26 January 2025

135

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Expressing what's on your mind: DNA arrays and the brain

26 January 2025

137

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Two Sites in the Delta Gene Region Contribute to Naturally Occurring Variation in Bristle Number in Drosophila melanogaster

26 January 2025

139

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Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations

26 January 2025

143

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Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations

26 January 2025

144

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Epistatic and environmental interactions for quantitative trait loci involved in maize evolution

26 January 2025

145

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Linkage disequilibrium mapping of molecular polymorphisms at the scabrous locus associated with naturally occurring variation in bristle number in Drosophila melanogaster

26 January 2025

147

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Candidate Quantitative Trait Loci and Naturally Occurring Phenotypic Variation for Bristle Number in Drosophila melanogaster: The Delta-Hairless Gene Region

26 January 2025

149

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Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping

26 January 2025

151

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Quantitative trait loci in Drosophila

26 January 2025

154

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Molecular and phenotypic variation in the achaete-scute region of Drosophila melanogaster

26 January 2025

157

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Estimating the locations and the sizes of the effects of quantitative trait loci using flanking markers

26 January 2025

160

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The manifold effect of selection

26 January 2025

162

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Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

26 January 2025

168

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Quantitative trait loci for growth traits in C57BL/6J x DBA/2J mice

26 January 2025

169

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A method for fine mapping quantitative trait loci in outbred animal stocks

26 January 2025

170

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Natural selection and the heritability of fitness components

26 January 2025

171

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Susceptibility locus for Alzheimer's disease on chromosome 10.

26 January 2025

172

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Modifier genes in mice and humans

26 January 2025

173

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The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs

26 January 2025

174

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Analysing complex genetic traits with chromosome substitution strains

26 January 2025

175

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DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene

26 January 2025

176

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A classical setting for associations between markers and loci affecting quantitative traits

26 January 2025

177

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A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

26 January 2025

179

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Polygenic mutation in Drosophila melanogaster: the causal relationship of bristle number to fitness.

26 January 2025

181

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The use of retrotransposons as markers for mapping genes responsible for fitness differences between related Drosophila melanogaster strains

26 January 2025

182

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Mapping quantitative trait loci affecting sternopleural bristle number in Drosophila melanogaster using changes of marker allele frequencies in divergently selected lines

26 January 2025

183

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster

26 January 2025

184

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The evolutionary genetics of adaptation: a simulation study

26 January 2025

186

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Mendelian factors underlying quantitative traits in tomato: comparison across species, generations, and environments.

26 January 2025

188

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Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms

26 January 2025

190

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Convergent domestication of cereal crops by independent mutations at corresponding genetic Loci

26 January 2025

191

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The Language of Gene Interaction

26 January 2025

192

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Naturally occurring genetic variation affects Drosophila photoreceptor determination

26 January 2025

193

1 reference

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Genetic dissection of obesity in polygenic animal models

26 January 2025

194

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

A Transmission Disequilibrium Test for Quantitative Trait Loci

26 January 2025

195

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Studies in quantitative inheritance. VI. Sternite chaeta number in Drosophila; a metameric quantitative character

26 January 2025

196

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The future of genetic studies of complex human diseases

26 January 2025

197

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Selection in animals: synthesis

26 January 2025

198

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https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Quantitative genetics and fitness: lessons from Drosophila

26 January 2025

205

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Hsp90 as a capacitor for morphological evolution

26 January 2025

207

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Marker-based mapping of quantitative trait loci using replicated progenies

26 January 2025

211

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On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines

26 January 2025

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Regular responses to selection. 3. Interaction between located polygenes

26 January 2025

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Identification of genetic factors contributing to heterosis in a hybrid from two elite maize inbred lines using molecular markers

26 January 2025

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Functional screening of an asthma QTL in YAC transgenic mice.

26 January 2025

220

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

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26 January 2025

221

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

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26 January 2025

222

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

26 January 2025

Mapping polygenes

223

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Genome sequence of the nematode C. elegans: a platform for investigating biology

26 January 2025

226

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

26 January 2025

227

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

26 January 2025

Location of Polygenes

228

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Mapping quantitative trait loci for murine growth: a closer look at genetic architecture

26 January 2025

230

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

The Sequence of the Human Genome

26 January 2025

231

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

A POPULATION GENETIC THEORY OF CANALIZATION.

26 January 2025

233

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

The limits of selection during maize domestication.

26 January 2025

235

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

On the number of segregating sites in genetical models without recombination

26 January 2025

236

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

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26 January 2025

240

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Direct allelic variation scanning of the yeast genome

26 January 2025

241

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

26 January 2025

242

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

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26 January 2025

243

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Combining Different Line Crosses for Mapping Quantitative Trait Loci Using the Identical by Descent-Based Variance Component Method

26 January 2025

245

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

A genetic map of Gibberella fujikuroi mating population A (Fusarium moniliforme)

26 January 2025

246

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

Estimating the genetic architecture of quantitative traits

26 January 2025

249

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

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26 January 2025

250

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.35.102401.090633

26 January 2025

Identifiers

1 reference

31 July 2017

1 reference