(Q34119060)

31 July 2017

title

Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasis (English)

1 reference

31 July 2017

1 reference

John D West

9

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Panagiotis Douvaras

object named as

Panagiotis Douvaras

5

0 references

Francis L Martin

object named as

Francis L Martin

3

0 references

Nigel J Fullwood

object named as

Nigel J Fullwood

8

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author name string

Richard L Mort

1

1 reference

31 July 2017

Adam J Bentley

2

1 reference

31 July 2017

J Martin Collinson

4

1 reference

31 July 2017

Robert E Hill

6

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31 July 2017

Steven D Morley

7

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31 July 2017

language of work or name

English

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publication date

29 December 2011

1 reference

31 July 2017

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31 July 2017

volume

6

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31 July 2017

issue

12

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31 July 2017

page(s)

e28895

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

29 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3248408/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Cytoskeletal and cell adhesion defects in wounded and Pax6+/- corneal epithelia

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Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium

5 July 2018

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Control of patterns of corneal innervation by Pax6.

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PAX6 dosage effects on corneal development, growth, and wound healing

5 July 2018

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Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

5 July 2018

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Cell surface glycoconjugate abnormalities and corneal epithelial wound healing in the pax6+/- mouse model of aniridia-related keratopathy

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The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6+/- mouse model of epithelial wound-healing delay

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Abnormal migration and distribution of neural crest cells in Pax6 heterozygous mutant eye, a model for human eye diseases.

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Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2

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Developmental and cellular factors underlying corneal epithelial dysgenesis in the Pax6+/- mouse model of aniridia

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Analysis of mouse eye development with chimeras and mosaics

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The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo

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Centripetal movement of corneal epithelial cells in the normal adult mouse

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PAX6 in sensory development

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Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye

5 July 2018

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Ultrastructural localization of sulfated and unsulfated keratan sulfate in normal and macular corneal dystrophy type I.

5 July 2018

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5 July 2018

PAX6 mutations reviewed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Cytologic evidence of corneal diseases with limbal stem cell deficiency.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia.

5 July 2018

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Cell lineage and the differentiation of corneal epithelial cells

5 July 2018

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Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Multiple functions for Pax6 in mouse eye and nasal development.

5 July 2018

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Stem cells and corneal epithelial regeneration

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

5 July 2018

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Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

5 July 2018

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The role of Pax-6 in eye and nasal development

5 July 2018

1 reference

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Measurement of centripetal migration of normal corneal epithelial cells in the mouse

5 July 2018

1 reference

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Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities.

5 July 2018

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Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Mouse small eye results from mutations in a paired-like homeobox-containing gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

The human PAX6 gene is mutated in two patients with aniridia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Tandem duplication of 11p12-p13 in a child with borderline development delay and eye abnormalities: dose effect of the PAX6 gene product?

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

21 January 2018

PAX6 mutations reviewed

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Gene transfer to ocular stem cells by early gestational intraamniotic injection of lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Missense mutations in the most ancient residues of the PAX6 paired domain underlie a spectrum of human congenital eye malformations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Histopathological characterisation of effects of the mouse Pax6(Leca4) missense mutation on eye development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Corneal Abnormalities inPax6+/−Small Eye Mice Mimic Human Aniridia-Related Keratopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Requirement for Pax6 in corneal morphogenesis: a role in adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Chronic wound state exacerbated by oxidative stress in Pax6+/- aniridia-related keratopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Intestinal stem cell replacement follows a pattern of neutral drift

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248408

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028895

Increased Apoptosis and Abnormal Wound-Healing Responses in the HeterozygousPax6+/−Mouse Cornea

21 January 2018

1 reference

12 December 2020

Functional identification of the actual and potential stem cell compartments in mouse spermatogenesis

1 reference

12 December 2020

Macular corneal dystrophy: ultrastructural pathology of corneal endothelium and Descemet's membrane

1 reference

12 December 2020

X-chromosome inactivation occurs at different times in different tissues of the post-implantation mouse embryo

1 reference

12 December 2020

Ocular surface abnormalities in aniridia

1 reference

12 December 2020

The cell shedding rate of the corneal epithelium--a comparison of collection methods

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12 December 2020

Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation

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12 December 2020

Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus

1 reference

12 December 2020

Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities

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12 December 2020

Management of aniridic keratopathy with keratolimbal allograft: a limbal stem cell transplantation technique

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0028895

Identifiers

DOI

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference