(Q34128162)

31 July 2017

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title

Cadherin and catenin alterations in human cancer (English)

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31 July 2017

Karen M Hajra

1

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PubMed ID

12007186

31 July 2017

Eric R Fearon

series ordinal

2

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31 July 2017

1 July 2002

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Genes, Chromosomes and Cancer

31 July 2017

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31 July 2017

34

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31 July 2017

255-268

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31 July 2017

3

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The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers

31 July 2017

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Inhibition of RhoA by p120 catenin

21 January 2018

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Regulated binding of PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of beta-catenin

21 January 2018

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The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

21 January 2018

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Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion

21 January 2018

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Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene

21 January 2018

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Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

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Mutations of the human E-cadherin (CDH1) gene.

21 January 2018

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beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer

21 January 2018

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Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo

21 January 2018

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The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

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Poorly differentiated colon carcinoma cell lines deficient in alpha-catenin expression express high levels of surface E-cadherin but lack Ca(2+)-dependent cell-cell adhesion

21 January 2018

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Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities

21 January 2018

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Transcriptional regulation of the human E-cadherin gene in human prostate cancer cell lines: characterization of the human E-cadherin gene promoter

21 January 2018

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

21 January 2018

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The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

21 January 2018

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A general theory of carcinogenesis

21 January 2018

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The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

21 January 2018

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The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor

21 January 2018

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Association of Human Protein-tyrosine Phosphatase κ with Members of the Armadillo Family

21 January 2018

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Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin

21 January 2018

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E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

21 January 2018

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Evidence for a function of CtBP in epithelial gene regulation and anoikis

21 January 2018

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E-cadherin germline mutations in familial gastric cancer.

21 January 2018

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The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton

21 January 2018

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Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis

21 January 2018

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Identification of c-MYC as a target of the APC pathway

21 January 2018

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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

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Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

21 January 2018

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Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

21 January 2018

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Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

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Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

21 January 2018

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E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

21 January 2018

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Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion

21 January 2018

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E-cadherin and its associated protein catenins, cancer invasion and metastasis

21 January 2018

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Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases.

21 January 2018

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c-erbB-2 gene product directly associates with beta-catenin and plakoglobin

21 January 2018

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Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells

21 January 2018

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Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the beta-catenin gene in a human cancer cell line, HSC-39

21 January 2018

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Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation

21 January 2018

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Axin directly interacts with plakoglobin and regulates its stability

21 January 2018

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Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis

21 January 2018

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Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

21 January 2018

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Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity

21 January 2018

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Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

21 January 2018

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Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex.

21 January 2018

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H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer

21 January 2018

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Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor).

21 January 2018

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

21 January 2018

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Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis

21 January 2018

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Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts

21 January 2018

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beta-catenin signaling and cancer

21 January 2018

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E-cadherin gene mutations in signet ring cell carcinoma of the stomach

21 January 2018

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Structural basis of calcium-induced E-cadherin rigidification and dimerization

21 January 2018

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N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression

21 January 2018

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Developmental biology. Making head or tail of Dickkopf.

21 January 2018

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c-erbB-2 gene product associates with catenins in human cancer cells.

21 January 2018

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Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line

21 January 2018

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The interactions and role of epithelial cadherin and catenins in tumorigenicity.

21 January 2018

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

21 January 2018

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A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions.

21 January 2018

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Mutations in the APC gene and their implications for protein structure and function

21 January 2018

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More than one way to skin a catenin

21 January 2018

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Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail

21 January 2018

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Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

21 January 2018

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Germline E-cadherin Gene (CDH1) Mutations Predispose to Familial Gastric Cancer and Colorectal Cancer

21 January 2018

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Mutations of the E-cadherin gene in human gynecologic cancers.

21 January 2018

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A mutation in alpha-catenin disrupts adhesion in clone A cells without perturbing its actin and beta-catenin binding activity

21 January 2018

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Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

21 January 2018

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The APC tumour suppressor has a nuclear export function.

21 January 2018

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The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

21 January 2018

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

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Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation

21 January 2018

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Simultaneous expression of cadherin-11 in signet-ring cell carcinoma and stromal cells of diffuse-type gastric cancer

21 January 2018

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Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line

21 January 2018

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

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Suppression of tumorigenicity by plakoglobin: an augmenting effect of N-cadherin.

21 January 2018

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Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

21 January 2018

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V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift

21 January 2018

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Cadherin cell adhesion receptors as a morphogenetic regulator

21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells.

21 January 2018

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Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

21 January 2018

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Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line

21 January 2018

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Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions

21 January 2018

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Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

21 January 2018

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Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.

21 January 2018

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Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

21 January 2018

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Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

21 January 2018

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APC gene: database of germline and somatic mutations in human tumors and cell lines

21 January 2018

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Complex cadherin expression in human prostate cancer cells

21 January 2018

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7 January 2021

Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene

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7 January 2021

BRCA1 and E-cadherin promoter hypermethylation and gene inactivation in cancer-association or mechanism?

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7 January 2021

Role of E boxes in the repression of E-cadherin expression

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7 January 2021

Changes in cadherin-catenin complexes in the progression of human bladder carcinoma

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7 January 2021

E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer

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7 January 2021

Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements

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7 January 2021

N-cadherin promotes adhesion between invasive breast cancer cells and the stroma.

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7 January 2021

Expression of E-cadherin, alpha-catenin, beta-catenin and plakoglobin in esophageal carcinomas and its prognostic significance: immunohistochemical analysis of 96 lesions

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7 January 2021

E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas

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7 January 2021

Identifiers

DOI

10.1002/GCC.10083

1 reference

31 July 2017

1 reference

PubMed ID

12007186