(Q34128457)

31 July 2017

1 reference

title

De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway (English)

1 reference

31 July 2017

1 reference

Alfred H Merrill

1

1 reference

PubMed ID

12011104

31 July 2017

language of work or name

English

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publication date

13 May 2002

1 reference

Journal of Biological Chemistry

31 July 2017

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31 July 2017

277

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31 July 2017

25843-25846

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31 July 2017

29

1 reference

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

31 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Combinatorial ganglioside biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Sphingolipid transport: rafts and translocators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

On the chemistry and occurrence of sphingolipid long-chain bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN). Nomenclature of glycolipids--recommendations 1997.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Sphingolipid synthesis: identification and characterization of mammalian cDNAs encoding the Lcb2 subunit of serine palmitoyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

SPTLC1 is mutated in hereditary sensory neuropathy, type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

A water-soluble homodimeric serine palmitoyltransferase from Sphingomonas paucimobilis EY2395T strain. Purification, characterization, cloning, and overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

The AMP-activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Dual video microscopic imaging of membrane potential and cytosolic calcium of immunoidentified embryonic rat cortical cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Endotoxin and cytokines increase hepatic sphingolipid biosynthesis and produce lipoproteins enriched in ceramides and sphingomyelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Production of ceramides causes apoptosis during early neural differentiation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Functional identification of a delta8-sphingolipid desaturase from Borago officinalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Identification and characterization of a sphingolipid delta 4-desaturase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Dihydroceramide delta(4) desaturase initiates substrate oxidation at C-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Syringomycin action gene SYR2 is essential for sphingolipid 4-hydroxylation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Functional characterization of sphingolipid C4-hydroxylase genes from Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Discovery and occurrence of the fumonisins: a historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Differential roles of de novo sphingolipid biosynthesis and turnover in the "burst" of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Ceramide mediates radiation-induced death of endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Ceramide: a new second messenger of cannabinoid action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

Enzymes of sphingolipid metabolism: from modular to integrative signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

BRS1, a C30 bis-amino, bis-hydroxy polyunsaturated lipid from an Australian calcareous sponge that inhibits protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R200009200

21 January 2018

Identifiers

DOI

10.1074/JBC.R200009200

1 reference

31 July 2017

1 reference

PubMed ID

12011104