(Q34141714)

31 July 2017

title

Routine dihydropyrimidine dehydrogenase testing for anticipating 5-fluorouracil-related severe toxicities: hype or hope? (English)

1 reference

31 July 2017

Routine Dihydropyrimidine Dehydrogenase Testing for Anticipating 5-Fluorouracil–Related Severe Toxicities: Hype or Hope? (English)

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

27 July 2024

1

Joseph Ciccolini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20920994

27 July 2024

author name string

Eva Gross

2

1 reference

31 July 2017

Laetitia Dahan

3

1 reference

31 July 2017

Bruno Lacarelle

4

1 reference

31 July 2017

Cédric Mercier

5

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 October 2010

1 reference

full work available at URL

31 July 2017

https://api.elsevier.com/content/article/PII:S1533002811700068?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

https://api.elsevier.com/content/article/PII:S1533002811700068?httpAccept=text/plain

27 July 2024

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Clinical Colorectal Cancer

27 July 2024

published in

1 reference

31 July 2017

volume

9

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31 July 2017

issue

4

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31 July 2017

page(s)

224-228

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Profiling dihydropyrimidine dehydrogenase deficiency in patients with cancer undergoing 5-fluorouracil/capecitabine therapy

31 July 2017

cites work

1

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

The role of Sp1 and Sp3 in the constitutive DPYD gene expression

27 July 2024

2

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Population study of dihydropyrimidine dehydrogenase in cancer patients

27 July 2024

3

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Severe or lethal toxicities upon capecitabine intake: is DPYD genetic polymorphism the ideal culprit?

27 July 2024

4

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity

27 July 2024

5

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Characterization of the human dihydropyrimidine dehydrogenase gene

27 July 2024

6

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity

27 July 2024

8

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects.

27 July 2024

9

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity

27 July 2024

10

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Two cases of 5-fluorouracil toxicity linked with gene variants in the DPYD gene.

27 July 2024

12

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Dihydropyrimidine dehydrogenase gene variation and severe 5-fluorouracil toxicity: a haplotype assessment.

27 July 2024

13

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

A high-throughput denaturing high-performance liquid chromatography method for the identification of variant alleles associated with dihydropyrimidine dehydrogenase deficiency

27 July 2024

14

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Rapid detection of the DPYD IVS14+1G>A mutation for screening patients to prevent fluorouracil-related toxicity

27 July 2024

15

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in a cohort of Caucasian individuals

27 July 2024

16

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group

27 July 2024

17

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance

27 July 2024

18

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

DPYD*5 gene mutation contributes to the reduced DPYD enzyme activity and chemotherapeutic toxicity of 5-FU: results from genotyping study on 75 gastric carcinoma and colon carcinoma patients

27 July 2024

19

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Known variant DPYD alleles do not explain DPD deficiency in cancer patients

27 July 2024

20

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

The contribution of deleterious DPYD gene sequence variants to fluoropyrimidine toxicity in British cancer patients

27 July 2024

21

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients

27 July 2024

22

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemothera

27 July 2024

23

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Predicting fluorouracil toxicity: can we finally do it?

27 July 2024

24

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Methylation of the DPYD promoter: an alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients

27 July 2024

25

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy

27 July 2024

26

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Toxicity and efficacy of 5-fluorouracil and capecitabine in a patient with TYMS gene polymorphism: A challenge or a dilemma?

27 July 2024

27

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Contribution of dihydropyrimidinase gene alterations to the development of serious toxicity in fluoropyrimidine-treated cancer patients

27 July 2024

28

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Genetic regulation of dihydropyrimidinase and its possible implication in altered uracil catabolism

27 July 2024

29

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Genetic regulation of beta-ureidopropionase and its possible implication in altered uracil catabolism

27 July 2024

30

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

A rapid and inexpensive method for anticipating severe toxicity to fluorouracil and fluorouracil-based chemotherapy

27 July 2024

31

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

27 July 2024

32

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients

27 July 2024

33

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

27 July 2024

34

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

The influence of fluorouracil outcome parameters on tolerance and efficacy in patients with advanced colorectal cancer

27 July 2024

35

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity

27 July 2024

38

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

27 July 2024

39

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences

27 July 2024

40

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Dihydropyrimidine dehydrogenase (DPD) deficiency: identification and expression of missense mutations C29R, R886H and R235W

27 July 2024

41

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Lethal 5-fluorouracil toxicity associated with a novel mutation in the dihydropyrimidine dehydrogenase gene

27 July 2024

42

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Identification of novel mutations in the dihydropyrimidine dehydrogenase gene in a Japanese patient with 5-fluorouracil toxicity

27 July 2024

43

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Germline mutation of dihydropyrimidine dehydrogenese gene among a Japanese population in relation to toxicity to 5-Fluorouracil

27 July 2024

44

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure

27 July 2024

45

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

27 July 2024

46

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Identification of three novel mutations in the dihydropyrimidine dehydrogenase gene associated with altered pre-mRNA splicing or protein function

27 July 2024

49

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Dihydropyrimidine dehydrogenase activity in 150 healthy Japanese volunteers and identification of novel mutations

27 July 2024

50

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in Chinese cancer patients

27 July 2024

51

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Pharmacokinetically guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes

27 July 2024

52

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

Multicenter Evaluation of a Novel Nanoparticle Immunoassay for 5-Fluorouracil on the Olympus AU400 Analyzer

27 July 2024

53

1 reference

https://api.crossref.org/works/10.3816/CCC.2010.N.033

27 July 2024

Identifiers

1 reference

release_wl6oviv45ncixkcg2omb22mqhi

31 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wl6oviv45ncixkcg2omb22mqhi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference