(Q34160186)

31 July 2017

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title

Genetically engineered rodent models of mammary gland carcinogenesis: an overview (English)

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31 July 2017

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P E Blackshear

1

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31 July 2017

language of work or name

English

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publication date

1 January 2001

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31 July 2017

published in

Toxicologic Pathology

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31 July 2017

volume

29

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31 July 2017

issue

1

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31 July 2017

page(s)

105-116

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Signal transduction pathway targets for anticancer drug discovery

31 July 2017

cites work

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Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice

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Tumor viruses and endogenous retrotransposons in mammary tumorigenesis

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Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

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The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors.

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The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting

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Signal transduction in mammary tumorigenesis: a transgenic perspective

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Development of hyperplasias, preneoplasias, and mammary tumors in MMTV-c-erbB-2 and MMTV-TGFalpha transgenic rats

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p21ras in carcinogenesis

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Mammary gland oncogenes as indicators of pathways important in mammary gland development

21 January 2018

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Chemically induced mammary gland cancer in the National Toxicology Program's carcinogenesis bioassay

21 January 2018

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Development of a flexible and specific gene delivery system for production of murine tumor models

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BRCA1 mutations in primary breast and ovarian carcinomas

21 January 2018

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Wnt signaling stabilizes the dual-function protein beta-catenin in diverse cell types

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Mechanism-based target identification and drug discovery in cancer research

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Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer

21 January 2018

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Current perspectives on radiation-induced breast cancer

21 January 2018

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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

21 January 2018

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The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma

21 January 2018

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Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

21 January 2018

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

21 January 2018

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Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression

21 January 2018

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IGF and insulin action in the mammary gland: lessons from transgenic and knockout models

21 January 2018

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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

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Transforming growth factor alpha and mouse models of human breast cancer

21 January 2018

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Tumor spectrum analysis in p53-mutant mice

21 January 2018

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Dual regulation of proliferation and apoptosis: c-myc in bitransgenic murine mammary tumor models

21 January 2018

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Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice.

21 January 2018

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Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

21 January 2018

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Antioncogenes and human cancer

21 January 2018

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Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

21 January 2018

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BRCA2 mutations in primary breast and ovarian cancers

21 January 2018

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Tumor suppressor genes and their alterations in breast cancer

21 January 2018

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neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

21 January 2018

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WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis

21 January 2018

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Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer

21 January 2018

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Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

21 January 2018

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

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Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

21 January 2018

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Insights into cancer from transgenic mouse models

21 January 2018

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

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BRCA1 Mutations and Breast Cancer in the General Population

21 January 2018

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Breast cancer incidence among atomic bomb survivors, Hiroshima and Nagasaki, 1950-69

21 January 2018

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Defining a role for c-Myc in breast tumorigenesis.

21 January 2018

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Matrix metalloproteinases: biologic activity and clinical implications

21 January 2018

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WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells

21 January 2018

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Growth factors: regulation of normal and neoplastic growth

21 January 2018

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HER-2/neu signal transduction in human breast and ovarian cancer

21 January 2018

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Transforming growth factor alpha- and c-myc-induced mammary carcinogenesis in transgenic mice

21 January 2018

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Dietary fatty acids and prevention of hormone-responsive cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development

21 January 2018

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Matrix metalloproteinases in remodeling of the normal and neoplastic mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Epidermal growth factor-related peptides and their receptors in human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Inducible gene targeting in mice using the Cre/lox system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F019262301301418919

Recent advances in understanding of genetic susceptibility to breast cancer

21 January 2018

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https://api.crossref.org/works/10.1080%2F019262301301418919

Function of the IGF-I receptor in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Low incidence of BRCA2 mutations in breast carcinoma and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Do hormones cause breast cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Prolactin gene-disruption arrests mammary gland development and retards T-antigen-induced tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Induction of mammary epithelial hyperplasias and mammary tumors in transgenic mice expressing a murine mammary tumor virus/activated c-src fusion gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Crosstalk between the insulin-like growth factors and estrogens in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

Alcohol and breast cancer in the Swiss Canton of Vaud

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F019262301301418919

10.1080/019262301301418919

21 January 2018

Identifiers

DOI

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31 July 2017

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