(Q34160954)

31 July 2017

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title

Clinical pharmacokinetics of sertraline (English)

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31 July 2017

sertraline hydrochloride

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ChEBI release 2020-05-28

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C Lindsay DeVane

1

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31 July 2017

Heidi L Liston

series ordinal

2

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31 July 2017

John S Markowitz

series ordinal

3

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31 July 2017

1 January 2002

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Clinical Pharmacokinetics

31 July 2017

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31 July 2017

41

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31 July 2017

1247-1266

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31 July 2017

15

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https://scigraph.springernature.com/pub.10.2165/00003088-200241150-00002

31 July 2017

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cites work

Plasma concentrations of clozapine and its major metabolites during combined treatment with paroxetine or sertraline

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12 December 2020

A study of the potential effect of sertraline on the pharmacokinetics and protein binding of tolbutamide

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12 December 2020

Therapeutic monitoring of sertraline

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12 December 2020

Absence of effect of sertraline on time-based sensitization of cognitive impairment with haloperidol.

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12 December 2020

Absence of a sertraline-mediated effect on the pharmacokinetics and pharmacodynamics of carbamazepine

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12 December 2020

Sertraline Does Not Alter Steady-State Concentrations or Renal Clearance of Lithium in Healthy Volunteers

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12 December 2020

Pharmacokinetics of sertraline in relation to genetic polymorphism of CYP2C19.

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12 December 2020

Comparison of desmethylsertraline with sertraline as a monoamine uptake inhibitor in vivo

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12 December 2020

On central effects of serotonin re-uptake inhibitors: quantitative EEG and psychometric studies with sertraline and zimelidine

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12 December 2020

Pharmacokinetics of desipramine coadministered with sertraline or fluoxetine

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12 December 2020

Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers

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12 December 2020

Sertraline and norsertraline levels in three breastfed infants.

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12 December 2020

Sertraline N-demethylation is catalyzed by multiple isoforms of human cytochrome P-450 in vitro.

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12 December 2020

Binding of antidepressants to human brain receptors: focus on newer generation compounds

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12 December 2020

Absence of a sertraline-mediated effect on digoxin pharmacokinetics and electrocardiographic findings

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12 December 2020

CYP2D6 inhibition in patients treated with sertraline.

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12 December 2020

Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes

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12 December 2020

Dose-response evaluation of the interaction between sertraline and alprazolam in vivo.

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12 December 2020

Gas chromatographic-mass spectrometric analysis and preliminary human pharmacokinetics of sertraline, a new antidepressant drug

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12 December 2020

Fluvoxamine but not sertraline inhibits the metabolism of olanzapine: evidence from a therapeutic drug monitoring service

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12 December 2020

Co-administration of sertraline and haloperidol

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12 December 2020

Sertraline pharmacokinetics and dynamics in adolescents

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12 December 2020

The effect of sertraline on the pharmacokinetics of desipramine and imipramine

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12 December 2020

CYP2D6 inhibition by fluoxetine, paroxetine, sertraline, and venlafaxine in a crossover study: intraindividual variability and plasma concentration correlations

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12 December 2020

Lamotrigine toxicity secondary to sertraline

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12 December 2020

Sertraline. Chronopharmacokinetics and the effect of coadministration with food.

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12 December 2020

Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors

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12 December 2020

Therapeutic drug monitoring of sertraline: variability factors as displayed in a clinical setting

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12 December 2020

Elevated serum phenytoin concentrations associated with coadministration of sertraline

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12 December 2020

Distribution of sertraline in postmortem cases

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12 December 2020

Clonazepam and sertraline: absence of drug interaction in a multiple-dose study

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12 December 2020

Effect of sertraline on protein binding of warfarin

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12 December 2020

Simultaneous determination of human plasma levels of four selective serotonin reuptake inhibitors by high-performance liquid chromatography

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12 December 2020

Human cytochromes mediating sertraline biotransformation: seeking attribution

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12 December 2020

The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin

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12 December 2020

Analysis of sertraline and desmethylsertraline in human plasma and red blood cells

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12 December 2020

Interactions between sertraline and tricyclic antidepressants

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12 December 2020

Lack of sertraline efficacy probably due to an interaction with carbamazepine

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12 December 2020

Sertraline and breast-feeding.

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12 December 2020

CYP2D6 status of extensive metabolizers after multiple-dose fluoxetine, fluvoxamine, paroxetine, or sertraline

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12 December 2020

Serum sertraline and N-desmethylsertraline levels in breast-feeding mother-infant pairs

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12 December 2020

Terfenadine-antidepressant interactions: an in vitro inhibition study using human liver microsomes

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12 December 2020

Pregnancy outcome following maternal use of the new selective serotonin reuptake inhibitors: a prospective controlled multicenter study.

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12 December 2020

Possible interaction of sertraline with carbamazepine

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12 December 2020

Pharmacokinetics of sertraline and its N-demethyl metabolite in elderly and young male and female volunteers.

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12 December 2020

Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites

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12 December 2020

Interaction of fluoxetine with tricyclic antidepressants

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12 December 2020

Lack of effect of sertraline on the pharmacokinetics of alprazolam

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12 December 2020

Possible interaction between sertraline and tranylcypromine

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12 December 2020

Pharmacokinetics of selective serotonin reuptake inhibitors

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12 December 2020

Paroxetine, sertraline, and fluvoxamine: new selective serotonin reuptake inhibitors

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12 December 2020

Sertraline treatment of children and adolescents with obsessive-compulsive disorder or depression: pharmacokinetics, tolerability, and efficacy

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12 December 2020

Separation and determination of sertraline and its metabolite, desmethylsertraline, in mouse cerebral cortex by reversed-phase high-performance liquid chromatography

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12 December 2020

Overdose and Safety with Fluvoxamine

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12 December 2020

The effects of grapefruit juice on sertraline metabolism: an in vitro and in vivo study

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12 December 2020

Influence of liver cirrhosis on sertraline pharmacokinetics.

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12 December 2020

Sertraline: a new antidepressant

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12 December 2020

The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors.

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12 December 2020

Hypoglycemia associated with high doses of sertraline and sulphonylurea compound in a noninsulin-dependent diabetes mellitus patient

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12 December 2020

Pharmacokinetics of the newer antidepressants: clinical relevance

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12 December 2020

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

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12 December 2020

Therapeutic drug monitoring of selective serotonin reuptake inhibitors influences clinical dosing strategies and reduces drug costs in depressed elderly patients

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12 December 2020

The effect of sertraline on methadone plasma levels in methadone-maintenance patients

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12 December 2020

Rifampin-induced selective serotonin reuptake inhibitor withdrawal syndrome in a patient treated with sertraline

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12 December 2020

Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction

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12 December 2020

Pharmacokinetics of the selective serotonin reuptake inhibitors

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12 December 2020

Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes.

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12 December 2020

Effect of sertraline on plasma nortriptyline levels in depressed elderly

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12 December 2020

The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes

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12 December 2020

Determination of sertraline and desmethylsertraline in human serum using copolymeric bonded-phase extraction, liquid chromatography and gas chromatography-mass spectrometry

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12 December 2020

Coadministration of short-term zolpidem with sertraline in healthy women

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12 December 2020

Sertraline does not inhibit cytochrome P450 3A-mediated drug metabolism in vivo

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12 December 2020

The serotonin syndrome

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12 December 2020

HPLC of sertraline and norsertraline in plasma or serum

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12 December 2020

Differential time course of cytochrome P450 2D6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers

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12 December 2020

The effect of selective serotonin reuptake inhibitors (SSRIs) on the pharmacokinetics and metabolism of perazine in the rat.

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12 December 2020

Distribution and excretion of sertraline and N-desmethylsertraline in human milk.

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12 December 2020

Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics

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12 December 2020

Hemodialyzability of sertraline

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12 December 2020

Interaction of sertraline with clozapine

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12 December 2020

Clinical pharmacokinetics of selective serotonin reuptake inhibitors

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12 December 2020

Comparison of the effects of sertraline and its metabolite desmethylsertraline on blockade of central 5-HT reuptake in vivo.

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12 December 2020

An interaction of sertraline and desipramine

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12 December 2020

CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

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12 December 2020

The influence of selective serotonin reuptake inhibitors (SSRIs) on the pharmacokinetics of thioridazine and its metabolites: in vivo and in vitro studies

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12 December 2020

Metabolism and disposition of the 5-hydroxytryptamine uptake blocker sertraline in the rat and dog.

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12 December 2020

Sertraline in paired blood plasma and breast-milk samples from nursing mothers

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12 December 2020

Sertraline and desmethylsertraline in human breast milk and nursing infants

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12 December 2020

Effect of sertraline on the pharmacokinetics and protein binding of diazepam in healthy volunteers.

1 reference

12 December 2020

Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial.

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12 December 2020

Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

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12 December 2020

Serotonin syndrome in a child associated with erythromycin and sertraline

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12 December 2020

Sertraline does not alter the beta-adrenergic blocking activity of atenolol in healthy male volunteers

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12 December 2020

Clinical Implications of the Pharmacology of Sertraline

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12 December 2020

10.2165/00003088-200241150-00002

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

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