(Q34175680)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Synthetic lethal screen of an EGFR-centered network to improve targeted therapies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Igor Astsaturov

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Vladimir Ratushny

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Anna Sukhanova

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Margret B Einarson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Tetyana Bagnyukova

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Yan Zhou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Karthik Devarajan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Nadezhda Tikhmyanova

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Natalya Skobeleva

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Anna Pecherskaya

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Rochelle E Nasto

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Catherine Sharma

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Sandra A Jablonski

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Ilya G Serebriiskii

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Louis M Weiner

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Erica A Golemis

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

publication date

21 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

ra67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

140

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

14 February 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2950064/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/2950064

inferred from PubMed Central ID database lookup

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Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death

5 July 2018

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5 July 2018

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EGFR signals to mTOR through PKC and independently of Akt in glioma

5 July 2018

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5 July 2018

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AIP regulates stability of Aurora-A at early mitotic phase coordinately with GSK-3beta.

5 July 2018

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Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.

5 July 2018

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Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer

5 July 2018

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PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.

5 July 2018

1 reference

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The BioGRID Interaction Database: 2008 update

5 July 2018

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Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

5 July 2018

1 reference

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Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior

5 July 2018

1 reference

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Synthetic lethal screen identification of chemosensitizer loci in cancer cells

5 July 2018

1 reference

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In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors

5 July 2018

1 reference

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Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

5 July 2018

1 reference

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Genetic screening for signal transduction in the era of network biology

5 July 2018

1 reference

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Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.

5 July 2018

1 reference

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Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors

5 July 2018

1 reference

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BioNetBuilder: automatic integration of biological networks

5 July 2018

1 reference

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Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

5 July 2018

1 reference

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PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.

5 July 2018

1 reference

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Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival

5 July 2018

1 reference

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A comprehensive pathway map of epidermal growth factor receptor signaling

5 July 2018

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

5 July 2018

1 reference

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KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

5 July 2018

1 reference

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p130Cas: a versatile scaffold in signaling networks

5 July 2018

1 reference

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Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia

5 July 2018

1 reference

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5 July 2018

1 reference

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The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

5 July 2018

1 reference

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Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras

5 July 2018

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CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.

5 July 2018

1 reference

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KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

5 July 2018

1 reference

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Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening.

5 July 2018

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5 July 2018

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5 July 2018

1 reference

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A census of human cancer genes

5 July 2018

1 reference

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Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells

5 July 2018

1 reference

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Cytoscape: a software environment for integrated models of biomolecular interaction networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Protein complexes and functional modules in molecular networks

5 July 2018

1 reference

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TM4: a free, open-source system for microarray data management and analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

The KEGG databases at GenomeNet

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

BIND--The Biomolecular Interaction Network Database

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

The docking protein HEF1 is an apoptotic mediator at focal adhesion sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

5 July 2018

1 reference

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Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Integrin signalling: a new Cas(t) of characters enters the stage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

From molecular to modular cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Emergence of Scaling in Random Networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Computing topological parameters of biological networks.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

GENETICS: Total Information Awareness for Worm Genetics

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950064

Mechanisms of tumor resistance to EGFR-targeted therapies

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20858866

12 December 2020

inferred from PubMed ID database lookup

Up-regulation of a mutant form of p53 by doxorubicin in human squamous carcinoma cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20858866

12 December 2020

inferred from PubMed ID database lookup

RO 31-8220 and RO 31-7549 show improved selectivity for protein kinase C over staurosporine in macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20858866

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCISIGNAL.2001083

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20858866%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference