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LPS induction of gene expression in human monocytes
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
LPS induction of gene expression in human monocytes
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
author name string
Guha M
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
Mackman N
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
publication date
1 February 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Cellular Signalling
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
volume
13
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
page(s)
85-94
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
cites work
Structure and function of lipopolysaccharide binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleotide sequence of the gene encoding the monocyte differentiation antigen, CD14.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice expressing human CD14 are hypersensitive to lipopolysaccharide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved signaling pathway: the Drosophila toll-dorsal pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptors in the induction of the innate immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling mechanisms in the antimicrobial host defense of Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of human receptors structurally related to Drosophila Toll
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tlr4: central component of the sole mammalian LPS sensor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear factor kappa B, a mediator of lipopolysaccharide effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unresponsiveness of MyD88-deficient mice to endotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SIGNAL TRANSDUCTION:IkB Kinases: Kinsmen with Different Crafts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide-induced tumor necrosis factor-alpha promoter activity is inhibitor of nuclear factor-kappaB kinase-dependent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IkappaB kinase signalsome activation and IkappaB proteolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limb and skin abnormalities in mice lacking IKKalpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-tyrosine kinase activation is required for lipopolysaccharide induction of interleukin 1beta and NFkappaB activation, but not NFkappaB nuclear translocation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor Necrosis Factor-α Activation of NF-κB Requires the Phosphorylation of Ser-471 in the Transactivation Domain of c-Rel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 regulates interleukin 1-induced nuclear factor kappaB activation in an inhibitory protein kappaBalpha-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Basal transcription factors TBP and TFIIB and the viral coactivator E1A 13S bind with distinct affinities and kinetics to the transactivation domain of NF-kappaB p65.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CREB-binding protein/p300 are transcriptional coactivators of p65
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pertussis toxin inhibition of B cell and macrophage responses to bacterial lipopolysaccharide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endotoxin signal transduction in macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide-induced tumor necrosis factor alpha production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Raf by ceramide-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A synthetic inhibitor of the mitogen-activated protein kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of ternary complex factor Elk-1 by MAP kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ERK2/p42 MAP kinase stimulates both autonomous and SRF-dependent DNA binding by Elk-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinase cascades as regulators of stress responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factors and mitogen-activated protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a mouse p21Cdc42/Rac activated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AP-1 function and regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p38 signal transduction pathway: activation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of p38 mitogen-activated protein kinase signaling pathway in the rapid induction of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Convergence of MAP kinase pathways on the ternary complex factor Sap-1a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PRAK, a novel protein kinase regulated by the p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of Egr-1/RelA synergy in distinguishing T cell activation from tumor necrosis factor-alpha-induced NF-kappa B1 transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2800%2900149-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0898-6568(00)00149-2
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
Fatcat ID
release_whlp7o77ancdfplben5yr7ecwe
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/whlp7o77ancdfplben5yr7ecwe
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
11257452
1 reference
stated in
Europe PubMed Central
PubMed ID
11257452
retrieved
31 July 2017
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