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Antigen processing by the proteasome
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1 reference
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Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
review article
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Europe PubMed Central
title
Antigen processing by the proteasome
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
author name string
Kloetzel PM
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
publication date
1 March 2001
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Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
published in
Nature Reviews Molecular Cell Biology
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Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
volume
2
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Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
page(s)
179-187
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Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
issue
3
1 reference
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Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
exact match
https://scigraph.springernature.com/pub.10.1038/35056572
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Structure and functions of the 20S and 26S proteasomes
1 reference
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7 January 2021
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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.
1 reference
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The base of the proteasome regulatory particle exhibits chaperone-like activity
1 reference
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7 January 2021
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Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26 S proteasome
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
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Functional analysis of the proteasome regulatory particle
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7 January 2021
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Structure of 20S proteasome from yeast at 2.4 A resolution
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution
1 reference
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7 January 2021
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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
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7 January 2021
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Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly
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7 January 2021
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Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
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Inactivation of a defined active site in the mouse 20S proteasome complex enhances major histocompatibility complex class I antigen presentation of a murine cytomegalovirus protein.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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MHC ligands and peptide motifs: first listing
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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The three-dimensional structure of peptide-MHC complexes
1 reference
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7 January 2021
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Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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Significance of the rapid degradation of newly synthesized proteins in mammalian cells: a working hypothesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Detecting and measuring cotranslational protein degradation in vivo
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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The major substrates for TAP in vivo are derived from newly synthesized proteins
1 reference
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7 January 2021
based on heuristic
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The 19S ring-type particles of Drosophila. Cytological and biochemical analysis of their intracellular association and distribution.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of cell proteins and the generation of MHC class I-presented peptides
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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20 S proteasomes are assembled via distinct precursor complexes. Processing of LMP2 and LMP7 proproteins takes place in 13-16 S preproteasome complexes
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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Sequence information within proteasomal prosequences mediates efficient integration of beta-subunits into the 20 S proteasome complex
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(beta 5i) incorporation into 20 S proteasomes
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes
1 reference
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7 January 2021
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Different proteasome subtypes in a single tissue exhibit different enzymatic properties.
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
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MHC class I antigen processing of an adenovirus CTL epitope is linked to the levels of immunoproteasomes in infected cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
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Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
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Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the proteasome activator REGalpha (PA28alpha)
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
A role for the proteasome regulator PA28alpha in antigen presentation
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
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The proteasome regulator PA28α/β can enhance antigen presentation without affecting 20S proteasome subunit composition
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired immunoproteasome assembly and immune responses in PA28-/- mice.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Double-cleavage production of the CTL epitope by proteasomes and PA28: role of the flanking region
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
A gated channel into the proteasome core particle
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
The high molecular weight multicatalytic proteinase, macropain, exists in a latent form in human erythrocytes
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the multicatalytic proteinase from rat skeletal muscle by fatty acids or sodium dodecyl sulphate
1 reference
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7 January 2021
based on heuristic
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The effect of heat shock on 20S/26S proteasomes.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for the activation of 20S proteasomes by 11S regulators
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition of the polyubiquitin proteolytic signal
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Existence of a molecular ruler in proteasomes suggested by analysis of degradation products
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abrogation of CTL Epitope Processing by Single Amino Acid Substitution Flanking the C-Terminal Proteasome Cleavage Site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation
1 reference
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https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A theoretical approach towards the identification of cleavage-determining amino acid motifs of the 20 S proteasome.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
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7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of proline residue for efficient production of MHC class I ligands by proteasomes
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An algorithm for the prediction of proteasomal cleavages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A kinetic model of vertebrate 20S proteasome accounting for the generation of major proteolytic fragments from oligomeric peptide substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SYFPEITHI: database for MHC ligands and peptide motifs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of viral interference with MHC class I antigen processing and presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HsN3 proteasomal subunit as a target for human immunodeficiency virus type 1 Nef protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the 26S proteasome by adenovirus E1A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation and TAP-mediated transport of peptides for major histocompatibility complex class I molecules.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of MHC class I--restricted antigen processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered peptidase and viral-specific T cell response in LMP2 mutant mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class I expression in mice lacking the proteasome subunit LMP-7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35056572
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35056572
1 reference
stated in
Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
Dimensions Publication ID
1001569345
0 references
PubMed ID
11265247
1 reference
stated in
Europe PubMed Central
PubMed ID
11265247
retrieved
31 July 2017
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