(Q34200058)

31 July 2017

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title

The insulin-like growth factor system and cancer (English)

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31 July 2017

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1

Derek LeRoith

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ORCID Public Data File 2021

31 July 2017

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author name string

Charles T Roberts

series ordinal

2

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PubMed ID

12767520

31 July 2017

language of work or name

English

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publication date

1 June 2003

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31 July 2017

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31 July 2017

195

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31 July 2017

127-137

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31 July 2017

2

1 reference

Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Use of mutagenesis to probe IGF-binding protein structure/function relationships.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Molecular and cellular aspects of the insulin-like growth factor I receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Role of insulin receptors and IGF receptors in growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

The IRS-1 signaling system

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https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Integrins and E-cadherin cooperate with IGF-I to induce migration of epithelial colonic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

The potentiation of estrogen on insulin-like growth factor I action in MCF-7 human breast cancer cells includes cell cycle components

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin and insulin-like growth factor I receptors utilize different G protein signaling components

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin-like growth factor I stimulates motility in human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Structure and autoregulation of the insulin-like growth factor 1 receptor kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Structural biology of insulin and IGF1 receptors: implications for drug design

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Serum insulin-like growth factor-I levels and prostate cancer risk--interpreting the evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

The IGF axis in the prostate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Systemic administration of insulin-like growth factor I (IGF-I) causes growth of the rat prostate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Serum insulin-like growth factor-1 is not a useful marker of prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin-like growth factor 1 (IGF-1), IGF-1 density, and IGF-1/PSA ratio for prostate cancer detection

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Insulin-Like Growth Factor I Is Not a Useful Marker of Prostate Cancer in Men with Elevated Levels of Prostate-Specific Antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins, and prostate cancer risk: a prospective study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Plasma insulin-like growth factor-I and serum IGF-binding protein 3 can be associated with the progression of breast cancer, and predict the risk of recurrence and the probability of survival in African-American and Hispanic women.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Obesity, weight change, fasting insulin, proinsulin, C-peptide, and insulin-like growth factor-1 levels in women with and without breast cancer: the Rancho Bernardo Study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

IGF-1, IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

A prospective study of insulin-like growth factor-I, IGF-binding proteins-1, -2 and -3 and lung cancer risk in women

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

The insulin-like growth factor I receptor gene is the target for the 15q26 amplicon in breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

1 reference

7 January 2021

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

Transcriptional regulation of insulin-like growth factor-I receptor gene expression in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

An alternative, nonapoptotic form of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2803%2900159-9

7 January 2021

10.1016/S0304-3835(03)00159-9

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

12767520