Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34201989)
Watch
English
The role of p53 in neuronal cell death
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The role of p53 in neuronal cell death
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
main subject
cell death
1 reference
based on heuristic
inferred from title
author name string
Morrison RS
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
Kinoshita Y
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
publication date
1 October 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
volume
7
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
page(s)
868-879
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
issue
10
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400741
0 references
cites work
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor spectrum analysis in p53-mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53: puzzle and paradigm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The complexity of p53 modulation: emerging patterns from divergent signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 in signaling checkpoint arrest or apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-induced apoptosis as a safeguard against cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Programmed cell death and the control of cell survival: lessons from the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in neurodegenerative disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICE, neuronal apoptosis and neurodegeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in neurodegenerative diseases: the role of mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kainic acid-induced apoptosis in rat striatum is associated with nuclear factor-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 induction is associated with neuronal damage in the central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear accumulation of p53 protein following kainic acid-induced seizures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-stimulation of cyclic-AMP-linked metabotropic glutamate receptors in rat striatum attenuates excitotoxin-induced nuclear factor-kappaB activation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Postinjury magnesium treatment attenuates traumatic brain injury-induced cortical induction of p53 mRNA in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 expression in brain after middle cerebral artery occlusion in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increase in p53 protein expression following cortical infarction in the spontaneously hypertensive rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of the Alzheimer amyloid beta protein by normal proteolytic processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-induced apoptosis: effect of hypoxic severity and role of p53 in neuronal cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Attenuation of p53 expression protects against focal ischemic damage in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of free radicals and p53 in neuron apoptosis in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-deficient mice are protected against adrenalectomy-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax involvement in p53-mediated neuronal cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for p53-mediated modulation of neuronal viability.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 is required for radiation-induced apoptosis in mouse thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Seizure susceptibility in DBA and C57 mice: the effects of various convulsants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential susceptibility to seizures induced by systemic kainic acid treatment in mature DBA/2J and C57BL/6J mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Behavioural analysis and susceptibility to CNS injury of four inbred strains of mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal stress and injury in C57/BL mice after systemic kainic acid administration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Connective tissue growth factor: a novel player in tissue reorganization after brain injury?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of HIV-1 gp120-induced apoptosis in neuroblastoma SK-N-SH cells by an antisense oligodeoxynucleotide against p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aging, energy, and oxidative stress in neurodegenerative diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of nitric oxide in neurodegenerative diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial permeability transition is a central coordinating event of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress in neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal cell death: a demise with different shapes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three distinct signalling responses by murine fibroblasts to genotoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEKK1/JNK signaling stabilizes and activates p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of neuronal survival by the serine-threonine protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BAX is required for neuronal death after trophic factor deprivation and during development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of NF-κB in p53-mediated programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of p53 as a sequence-specific DNA-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 binds to the TATA-binding protein and represses transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Twenty years of p53 research: structural and functional aspects of the p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of the growth inhibitor IGF-binding protein 3 by p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model for p53-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila p53 binds a damage response element at the reaper locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 negatively regulates the expression of a microtubule-associated protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Movement of Bax from the cytosol to mitochondria during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformation of the Bax C-terminus regulates subcellular location and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xS and Bax induce different apoptotic pathways in PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glyceraldehyde-3-phosphate dehydrogenase antisense oligodeoxynucleotides protect against cytosine arabinonucleoside-induced apoptosis in cultured cerebellar neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and classification of p53-regulated genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation and function of the p53-related proteins: same family, different rules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p53 induction and DNA damage in hippocampal granule cells after adrenalectomy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes of p53 in the brains of patients with Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cerebellar neurodegeneration in human hereditary DNA repair disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor suppressor p53 and its response gene p21WAF1/Cip1 are not markers of neuronal death following transient global cerebral ischemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The involvement of p53 in dopamine-induced apoptosis of cerebellar granule neurons and leukemic cells overexpressing p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 protein in sympathetic neurons: cytoplasmic localization and no apparent function in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400741
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4400741
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
PubMed ID
11279532
1 reference
stated in
Europe PubMed Central
PubMed ID
11279532
retrieved
31 July 2017
ResearchGate publication ID
12053053
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit