(Q34225877)

31 July 2017

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title

Host defense, viruses and apoptosis (English)

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31 July 2017

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G N Barber

1

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31 July 2017

1 February 2001

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Cell Death & Differentiation

31 July 2017

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31 July 2017

8

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31 July 2017

113-126

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31 July 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400823

31 July 2017

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7 January 2021

Natural killer cells in antiviral defense: function and regulation by innate cytokines

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7 January 2021

How to induce involuntary suicide: the need for dipeptidyl peptidase I.

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7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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7 January 2021

Cell suicide for beginners

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7 January 2021

Programmed cell death and the caspases.

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7 January 2021

Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases

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7 January 2021

Death receptors: signaling and modulation

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7 January 2021

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

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7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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7 January 2021

Modulation of life and death by the TNF receptor superfamily

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

IAP family proteins--suppressors of apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

NF-kappaB to the rescue: RELs, apoptosis and cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Role of NF-κB in p53-mediated programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

NF-kappa B inhibition causes spontaneous apoptosis in Epstein-Barr virus-transformed lymphoblastoid cells

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Virus-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Viruses and Apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Inhibition of virus-induced neuronal apoptosis by Bax.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The nature of the principal type 1 interferon-producing cells in human blood

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Natural interferon alpha/beta-producing cells link innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Functional role of type I and type II interferons in antiviral defense

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Virus interference. I. The interferon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

JNK2 and IKKbeta are required for activating the innate response to viral infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Increased Susceptibility of Cells Treated with Interferon to the Toxicity of Polyriboinosinic·Polyribocytidylic Acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Specificity of interferon-induced enhancement of toxicity for double-stranded ribonucleic acids.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Type I interferons are essential mediators of apoptotic death in virally infected cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Double-stranded RNA and interferon action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The 2-5A system: a personal view

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Triggering the interferon response: the role of IRF-3 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The growing family of interferon regulatory factors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Regulation of type I interferon gene expression by interferon regulatory factor-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The IRF-3 transcription factor mediates Sendai virus-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

IRF-1 is an essential mediator in IFN-gamma-induced cell cycle arrest and apoptosis of primary cultured hepatocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Sendai virus blocks alpha interferon signaling to signal transducers and activators of transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The Epstein-Barr virus latency BamHI-Q promoter is positively regulated by STATs and Zta interference with JAK/STAT activation leads to loss of BamHI-Q promoter activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

PKR; a sentinel kinase for cellular stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

PKR, apoptosis and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Activation of the IFN-inducible enzyme RNase L causes apoptosis of animal cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

The TRAIL to selective tumor death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Fas antigen (CD95) in pure erythroid cell line AS-E2 is induced by interferon-gamma and tumor necrosis factor-alpha and potentiates apoptotic death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Interferon-modulated expression of genes encoding the nuclear-dot-associated proteins Sp100 and promyelocytic leukemia protein (PML)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Proto-oncogene PML controls genes devoted to MHC class I antigen presentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

PML induces a novel caspase-independent death process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

PML is essential for multiple apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

1 reference

7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Regulation of apoptosis by viral gene products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

p53 inhibition by the LANA protein of KSHV protects against cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Regulation of the interferon-induced PKR: can viruses cope?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Viral interference with apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Apoptosis in HIV infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

AIDS and the death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Mechanism of interferon beta-induced squamous differentiation and programmed cell death in human non-small-cell lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Induction of apoptotic cell death in non-melanoma skin cancer by interferon-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Treatment of adult T-cell leukemia-lymphoma with a combination of interferon alfa and zidovudine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Recent developments in the virus therapy of cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Reovirus therapy of tumors with activated Ras pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Replicative adenoviruses for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Type I interferons keep activated T cells alive

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Interferon γ Induces the Expression of p21waf-1 and Arrests Macrophage Cell Cycle, Preventing Induction of Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400823

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400823

1 reference

PubMed ID

11313713

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11313713