(Q34232423)

31 July 2017

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title

Toxicogenetics in drug development (English)

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31 July 2017

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Park BK

1

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31 July 2017

Pirmohamed M

series ordinal

2

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31 July 2017

publication date

1 March 2001

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31 July 2017

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31 July 2017

volume

120

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31 July 2017

issue

1-3

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31 July 2017

page(s)

281-291

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Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

31 July 2017

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Stereoselective interaction between the R enantiomer of warfarin and cimetidine

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Evolving pattern of drug-induced toxic epidermal necrolysis.

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Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins

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The purine path to chemotherapy

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Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

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7 January 2021

Cytochrome P450 polymorphisms are associated with reduced warfarin dose

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7 January 2021

Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine

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7 January 2021

Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions

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7 January 2021

The effect of genetic polymorphisms in CYP2C9 on sulphamethoxazole N-hydroxylation.

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7 January 2021

Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity

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7 January 2021

Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms.

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7 January 2021

The immunogenetics of human infectious diseases

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7 January 2021

Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment

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7 January 2021

Human P450 metabolism of warfarin

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7 January 2021

Pharmacogenetics of Cancer Therapy: Getting Personal

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7 January 2021

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

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7 January 2021

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

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Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

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7 January 2021

Genetics in drug discovery and development: challenge and promise of individualizing treatment in common complex diseases

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7 January 2021

Getting the right drug into the right patient

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7 January 2021

Plasma cysteine deficiency and decreased reduction of nitrososulfamethoxazole with HIV infection

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7 January 2021

Pharmacogenetics and pharmacogenomics: why is this relevant to the clinical geneticist?

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7 January 2021

Idiosyncratic drug reactions: a mechanistic evaluation of risk factors

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7 January 2021

Relevance of induction of human drug-metabolizing enzymes: pharmacological and toxicological implications

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7 January 2021

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

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7 January 2021

Adverse drug reactions

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7 January 2021

Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity

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7 January 2021

Prominence of slow acetylator phenotype among patients with sulfonamide hypersensitivity reactions

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7 January 2021

Pharmacogenetics and the practice of medicine

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7 January 2021

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient

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7 January 2021

Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk

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7 January 2021

Genetic predisposition to phenytoin-induced birth defects

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7 January 2021

Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes

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7 January 2021

Interpretation of results from genetic studies of multifactorial diseases

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7 January 2021

Adverse reactions to co-trimoxazole in HIV infection

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7 January 2021

Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

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7 January 2021

Genetic traits in common diseases

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7 January 2021

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7 January 2021

Science, medicine, and the future: Pharmacogenetics

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7 January 2021

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Identifiers

DOI

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31 July 2017

1 reference