(Q34245363)

31 July 2017

Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans (English)

1 reference

31 July 2017

Bernhard Bielesz

1

0 references

Katalin Susztak

object named as

Katalin Susztak

11

0 references

Volker H. Haase

object named as

Volker H Haase

10

0 references

Manfred Gessler

object named as

Manfred Gessler

9

0 references

author name string

Yasemin Sirin

2

1 reference

31 July 2017

Han Si

3

1 reference

31 July 2017

Thiruvur Niranjan

4

1 reference

31 July 2017

Antje Gruenwald

5

1 reference

31 July 2017

Seonho Ahn

6

1 reference

31 July 2017

Hideki Kato

7

1 reference

31 July 2017

James Pullman

8

1 reference

31 July 2017

language of work or name

English

0 references

publication date

18 October 2010

1 reference

Journal of Clinical Investigation

31 July 2017

1 reference

31 July 2017

120

1 reference

31 July 2017

4040-4054

1 reference

31 July 2017

11

1 reference

TGFbeta signalling: a complex web in cancer progression

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Differential expression of claudin tight junction proteins in the human cortical nephron

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

EMT: when epithelial cells decide to become mesenchymal-like cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Intrinsic epithelial cells repair the kidney after injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Ectopic notch activation in developing podocytes causes glomerulosclerosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Molecular insights into segmentation along the proximal-distal axis of the nephron.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch signaling is necessary for epithelial growth arrest by TGF-beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Hypoxia requires notch signaling to maintain the undifferentiated cell state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

The role of Notch signaling in specification of podocyte and proximal tubules within the developing mouse kidney.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Direct regulation of intestinal fate by Notch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Epithelial-mesenchymal transition and its implications for fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Evidence that fibroblasts derive from epithelium during tissue fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

A role for Wnt-4 in renal fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

How does podocyte damage result in tubular damage?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Disruption of the mouse RBP-J kappa gene results in early embryonic death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Tubulointerstitial changes as a major determinant in the progression of renal damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Uremic memory: the role of acute kidney injury in long-term outcomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

The Notch pathway in podocytes plays a role in the development of glomerular disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978353

12 December 2020

inferred from PubMed ID database lookup

The pathogenic role of Notch activation in podocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978353

12 December 2020

inferred from PubMed ID database lookup

State-specific trends in chronic kidney failure--United States, 1990-2001

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978353

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1172/JCI43025

1 reference

release_zdahpkhj2redvdqgj3efnhun5a

31 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zdahpkhj2redvdqgj3efnhun5a

24 November 2022

mapped directly with Wikidata item

PMCID

2964979

1 reference

31 July 2017

1 reference