(Q34254621)

31 July 2017

1 reference

title

Regulation of cellular senescence by p53. (English)

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31 July 2017

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K Itahana

1

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31 July 2017

G Dimri

series ordinal

2

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31 July 2017

J Campisi

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

1 May 2001

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31 July 2017

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31 July 2017

268

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31 July 2017

2784-2791

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31 July 2017

10

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The serial cultivation of human diploid cell strains

31 July 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Cellular senescence: mitotic clock or culture shock?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Cellular senescence revisited: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Telomere end-replication problem and cell aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Oxidative DNA damage and senescence of human diploid fibroblast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

PML suppresses oncogenic transformation of NIH/3T3 cells by activated neu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Microarray analysis of replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Cataloging altered gene expression in young and senescent cells using enhanced differential display

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Senescence as a mode of tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Overcoming cellular senescence in human cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Replicative senescence: an old lives' tale?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Aging and cancer: the double-edged sword of replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Reinitiation of host DNA synthesis in senescent human diploid cells by infection with simian virus 40

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Progress of aging in human diploid cells transformed with a tsA mutant of simian virus 40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI-38 cells by simian virus 40 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Preneoplastic transformation of human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Repair of telomeric DNA prior to replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Accelerated telomere shortening in ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Ku is associated with the telomere in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Increased activity of p53 in senescing fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Investigation of the role of G1/S cell cycle mediators in cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Increased p53 protein associated with aging in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02228.X

10.1046/J.1432-1327.2001.02228.X

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference