(Q34272451)

1 August 2017

Neuronal network of panic disorder: the role of the neuropeptide cholecystokinin (English)

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1 August 2017

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P Zwanzger

1

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PubMed ID

22553078

1 August 2017

K Domschke

series ordinal

2

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PubMed ID

22553078

1 August 2017

J Bradwejn

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3

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1 August 2017

2 May 2012

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1 August 2017

Depression and Anxiety

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1 August 2017

29

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1 August 2017

762-774

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1 August 2017

9

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Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey

1 August 2017

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The cross-national epidemiology of panic disorder

21 January 2018

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Lifetime panic-depression comorbidity in the National Comorbidity Survey. Association with symptoms, impairment, course and help-seeking

21 January 2018

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Neuroanatomical hypothesis of panic disorder, revised

21 January 2018

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Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology

21 January 2018

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Recent advances in the neurobiology of anxiety disorders: implications for novel therapeutics

21 January 2018

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The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology

21 January 2018

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New peptide in the vertebrate CNS reacting with antigastrin antibodies

21 January 2018

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Neuronal cholecystokinin: one or multiple transmitters?

21 January 2018

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Two brain cholecystokinin receptors: implications for behavioral actions.

21 January 2018

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Cholecystokinin-tetrapeptide induces panic attacks in patients with panic disorder

21 January 2018

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Enhanced sensitivity to cholecystokinin tetrapeptide in panic disorder. Clinical and behavioral findings

21 January 2018

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Sensitivity to cholecystokinin-tetrapeptide in major depression

21 January 2018

1 reference

Effects of CCK-tetrapeptide in patients with social phobia and obsessive-compulsive disorder

21 January 2018

1 reference

The cholecystokinin hypothesis of anxiety and panic disorder

21 January 2018

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Effects of tiagabine on cholecystokinin-tetrapeptide (CCK-4)-induced anxiety in healthy volunteers

21 January 2018

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Cholecystokinin tetrapeptide induces panic-like attacks in healthy volunteers. Preliminary findings.

21 January 2018

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Evaluation of the CCK-4 model as a challenge paradigm in a population of healthy volunteers within a proof-of-concept study

21 January 2018

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Vigabatrin decreases cholecystokinin-tetrapeptide (CCK-4) induced panic in healthy volunteers

21 January 2018

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Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder

21 January 2018

1 reference

Randomized, double-blind study of SR142801 (Osanetant). A novel neurokinin-3 (NK3) receptor antagonist in panic disorder with pre- and posttreatment cholecystokinin tetrapeptide (CCK-4) challenges

21 January 2018

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Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

21 January 2018

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Effects of a metabotropic glutamate(2/3) receptor agonist (LY544344/LY354740) on panic anxiety induced by cholecystokinin tetrapeptide in healthy humans: preliminary results

21 January 2018

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The acute antipanic activity of aerobic exercise

21 January 2018

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The acute antipanic and anxiolytic activity of aerobic exercise in patients with panic disorder and healthy control subjects

21 January 2018

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The selective serotonin re-uptake inhibitor escitalopram modulates the panic response to cholecystokinin tetrapeptide in healthy men depending on 5-HTTLPR genotype

21 January 2018

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Placebo-controlled trial of the CCK-B antagonist, CI-988, in panic disorder

21 January 2018

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Cholecystokinin-, galanin-, and corticotropin-releasing factor-like immunoreactive projections from the nucleus of the solitary tract to the parabrachial nucleus in the rat

21 January 2018

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Brainstem projection to the hypothalamic ventromedial nucleus in the rat: a CCK-containing long ascending pathway.

21 January 2018

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Cholecystokinin in the hypothalamo-hypophyseal system

21 January 2018

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Coexistence of substance P- and cholecystokinin-like immunoreactivity in neurons of the mesencephalic periaqueductal central gray

21 January 2018

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Origin of the cholecystokinin-containing fibers in the rat caudatoputamen.

21 January 2018

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Cholecystokinin corticostriatal pathway in the rat: evidence for bilateral origin from medial prefrontal cortical areas

21 January 2018

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Neuroanatomic correlates of CCK-4-induced panic attacks in healthy humans: a comparison of two time points.

21 January 2018

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The effect of cholecystokinin tetrapeptide on respiratory resistance in healthy volunteers.

21 January 2018

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Functional magnetic resonance imaging characterization of CCK-4-induced panic attack and subsequent anticipatory anxiety.

21 January 2018

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Functional neuroanatomy of CCK-4-induced panic attacks in healthy volunteers

21 January 2018

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Behavioral, cardiovascular, and neuroendocrine profiles following CCK-4 challenge in healthy volunteers: a comparison of panickers and nonpanickers.

21 January 2018

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Increased ACTH concentrations associated with cholecystokinin tetrapeptide-induced panic attacks in patients with panic disorder.

21 January 2018

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Effects of propranolol on symptom and endocrine responses to pentagastrin

21 January 2018

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Acute cholecystokinin effects on event-related potentials in healthy volunteers

21 January 2018

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Effects of acute cholecystokinin infusion on hemispheric EEG asymmetry and coherence in healthy volunteers

21 January 2018

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Cholecystokinin in the central nervous system

21 January 2018

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Autoradiographic Localization of Cholecystokinin A and B Receptors in Rat Brain Using [125I]d-Tyr25 (Nle28,31)-CCK 25 - 33S.

21 January 2018

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Differential Gene Expression of CCK(A) and CCK(B) Receptors in the Rat Brain.

21 January 2018

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On the distribution of cholecystokinin B receptors in monkey brain.

21 January 2018

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The role of the amygdala in fear and anxiety

21 January 2018

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Characterization of mice lacking the gene for cholecystokinin.

21 January 2018

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Different pathways mediated by CCK1 and CCK2 receptors: effect of intraperitonal mrna antisense oligodeoxynucleotides to cholecystokinin on anxiety-like and learning behaviors in rats

21 January 2018

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Inhibition of anxiety in rats by antisense to cholecystokinin precursor protein.

21 January 2018

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Increased anxiety behavior in OLETF rats without cholecystokinin-A receptor

21 January 2018

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Pharmacological evaluation of IQM-95,333, a highly selective CCKA receptor antagonist with anxiolytic-like activity in animal models

21 January 2018

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The effects of CCKA and CCKB antagonists on activity in the black/white exploration model of anxiety in mice.

21 January 2018

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21 January 2018

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Evidence for potentiation by CCK antagonists of the effect of cholecystokinin octapeptide in the elevated plus-maze.

21 January 2018

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Ethological analysis of cholecystokinin (CCKA and CCKB) receptor ligands in the elevated plus-maze test of anxiety in mice.

21 January 2018

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'Anxiolytic' effect of CCK-antagonists on plus-maze behavior in mice.

21 January 2018

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The effects of cholecystokinin A and B receptor antagonists on exploratory behaviour in the elevated zero-maze in rat.

21 January 2018

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Anxiety-like behavior and locomotion in CCK1 knockout rats as a function of strain, sex and early maternal environment.

21 January 2018

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Targeted invalidation of CCK2 receptor gene induces anxiolytic-like action in light-dark exploration, but not in fear conditioning test

21 January 2018

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Reduced anxious behavior in mice lacking the CCK2 receptor gene.

21 January 2018

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Targeted mutation of CCK2 receptor gene modifies the behavioural effects of diazepam in female mice

21 January 2018

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Behavioral effects of CCKB receptor ligands in a validated simulation of panic anxiety in rats.

21 January 2018

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Pharmacogenetic study of anxiolytic effects of new cholecystokinin receptor antagonists in animals with different levels of emotionality

21 January 2018

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Suppression of conditioned fear by administration of CCKB receptor antagonist PD135158.

21 January 2018

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Cholecystokinin dipeptoid antagonists: design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and "mixed" CCK-A/CCK-B antagonists

21 January 2018

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The antagonism of benzodiazepine withdrawal effects by the selective cholecystokininB receptor antagonist CI-988

21 January 2018

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The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist

21 January 2018

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Anxiolytic effects of CCK-B antagonists

21 January 2018

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Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.

21 January 2018

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Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity

21 January 2018

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Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse

21 January 2018

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Bi-directional effect of cholecystokinin receptor-2 overexpression on stress-triggered fear memory and anxiety in the mouse

21 January 2018

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Involvement of dorsolateral periaqueductal gray cholecystokinin-2 receptors in the regulation of a panic-related behavior in rats.

21 January 2018

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Systemic and intra-dorsal periaqueductal gray injections of cholecystokinin sulfated octapeptide (CCK-8s) induce a panic-like response in rats submitted to the elevated T-maze

21 January 2018

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Anxiogenic Effect of Cholecystokinin in the Dorsal Periaqueductal Gray

21 January 2018

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Role of cholecystokinin-A and cholecystokinin-B receptors in anxiety

21 January 2018

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Effect of the selective CCKB receptor antagonist LY288513 on conditioned fear stress in rats.

21 January 2018

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Suppression of conditioned fear by administration of CCKB receptor antisense oligodeoxynucleotide into the lateral ventricle.

21 January 2018

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Blockade of CRF1 and CCK2 receptors attenuated the elevated anxiety-like behavior induced by immobilization stress.

21 January 2018

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Decreased CCK(B) receptor binding in rat amygdala in animals demonstrating greater anxiety-like behavior.

21 January 2018

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Behavioral profile of CCK2 receptor-deficient mice.

21 January 2018

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Behavioural differences between C57BL/6 and 129S6/SvEv strains are reinforced by environmental enrichment.

21 January 2018

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Different housing conditions alter the behavioural phenotype of CCK(2) receptor-deficient mice.

21 January 2018

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PD135158, a CCK-B antagonist, reduces "state," but not "trait" anxiety in mice.

21 January 2018

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Heterogeneity of CCK-B receptors involved in animal models of anxiety

21 January 2018

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Pharmacology of a cholecystokinin receptor on 5-hydroxytryptamine neurones in the dorsal raphe of the rat brain

21 January 2018

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Effect of cholecystokinin tetrapeptide amide on the metabolism of 5-hydroxytryptamine in the rat brain.

21 January 2018

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Effects of BOC-CCK-4 and L 365.260 on cortical 5-HT release in guinea-pigs on exposure to the elevated plus maze

21 January 2018

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Cholecystokinin release mediated by 5-HT3 receptors in rat cerebral cortex and nucleus accumbens

21 January 2018

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Inhibition by 5-HT3 receptor antagonists of release of cholecystokinin-like immunoreactivity from the frontal cortex of freely moving rats.

21 January 2018

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Ondansetron, an antagonist of 5-HT3 receptors, antagonizes the anti-exploratory effect of caerulein, an agonist of CCK receptors, in the elevated plus-maze.

21 January 2018

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Association between serotonin-related genetic polymorphisms and CCK-4-induced panic attacks with or without 5-hydroxytryptophan pretreatment in healthy volunteers

21 January 2018

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Effect of acute tryptophan depletion on behavioral, cardiovascular, and hormonal sensitivity to cholecystokinin-tetrapeptide challenge in healthy volunteers.

21 January 2018

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Association testing of panic disorder candidate genes using CCK-4 challenge in healthy volunteers

21 January 2018

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Molecular targets in the treatment of anxiety

21 January 2018

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SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder

21 January 2018

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Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.

21 January 2018

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Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy

21 January 2018

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Benzodiazepines antagonize cholecystokinin-induced activation of rat hippocampal neurones

21 January 2018

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Induced panic attacks shift gamma-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results

21 January 2018

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Panic induction with cholecystokinin-tetrapeptide (CCK-4) Increases plasma concentrations of the neuroactive steroid 3alpha, 5alpha tetrahydrodeoxycorticosterone (3alpha, 5alpha-THDOC) in healthy volunteers

21 January 2018

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Changes in CCK-4 induced panic after treatment with the GABA-reuptake inhibitor tiagabine are associated with an increase in 3alpha,5alpha-tetrahydrodeoxycorticosterone concentrations.

21 January 2018

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Plasma gamma-amino-butyric acid (GABA) levels in cholecystokinine-tetrapeptide (CCK-4) induced anxiety

21 January 2018

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Release of cholecystokinin from rat cerebral cortex in vivo: role of GABA and glutamate receptor systems.

21 January 2018

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Long-term diazepam treatment produces changes in cholecystokinin receptor binding in rat brain.

21 January 2018

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The benzodiazepine antagonist flumazenil blocks the effects of CCK receptor agonists and antagonists in the elevated plus-maze.

21 January 2018

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Facilitation of GABA release by cholecystokinin and caerulein in rat cerebral cortex.

21 January 2018

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Cholecystokinin-GABA interactions in rat striatum.

21 January 2018

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Cholecystokinin-8S increases dynorphin B, aspartate and glutamate release in the fronto-parietal cortex of the rat via different receptor subtypes

21 January 2018

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Effects of cholecystokinin tetrapeptide (CCK(4)) and of anxiolytic drugs on GABA outflow from the cerebral cortex of freely moving rats

21 January 2018

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CCK4-induced panic in healthy subjects I: psychological and cardiovascular effects.

21 January 2018

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CCK-4: Psychophysiological conditioning elicits features of spontaneous panic attacks

21 January 2018

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Dose response of adrenocorticotropin and cortisol to the CCK-B agonist pentagastrin

21 January 2018

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Expression of neuropeptide Y and cholecystokinin in the rat brain by chronic mild stress

21 January 2018

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Neuropeptide S receptor induces neuropeptide expression and associates with intermediate phenotypes of functional gastrointestinal disorders

21 January 2018

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Melatonin MT(1/2) receptor stimulation reduces cortical overflow of cholecystokinin-like material in a model of anticipation of social defeat in the rat.

21 January 2018

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Cannabinoid CB1 and cholecystokinin CCK2 receptors modulate, in an opposing way, electrically evoked [3H]GABA efflux from rat cerebral cortex cell cultures: possible relevance for cortical GABA transmission and anxiety

21 January 2018

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Functional interactions between endocannabinoid and CCK neurotransmitter systems may be critical for extinction learning

21 January 2018

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GABAergic and endocannabinoid dysfunction in anxiety - future therapeutic targets?

21 January 2018

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Genetics of panic disorder: focus on association studies and therapeutic perspectives

21 January 2018

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Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity.

21 January 2018

1 reference

Association studies of MAO-A, COMT, and 5-HTT genes polymorphisms in patients with anxiety disorders of the phobic spectrum

21 January 2018

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Association study of 90 candidate gene polymorphisms in panic disorder

21 January 2018

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Neuropeptide S receptor gene -- converging evidence for a role in panic disorder.

21 January 2018

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Function of the C-36 to T polymorphism in the human cholecystokinin gene promoter

21 January 2018

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Investigation of cholecystokinin system genes in panic disorder.

21 January 2018

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Association studies of the CT repeat polymorphism in the 5' upstream region of the cholecystokinin B receptor gene with panic disorder and schizophrenia in Japanese subjects

21 January 2018

1 reference

Identification of a compound short tandem repeat stretch in the 5'-upstream region of the cholecystokinin gene, and its association with panic disorder but not with schizophrenia.

21 January 2018

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Transcriptional activities of cholecystokinin promoter haplotypes and their relevance to panic disorder susceptibility.

21 January 2018

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Association between the CCK-A receptor gene and panic disorder.

21 January 2018

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Association of cholecystokinin-A receptor gene polymorphisms and panic disorder in Japanese.

21 January 2018

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Association studies of the cholecystokinin B receptor and A2a adenosine receptor genes in panic disorder

21 January 2018

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Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment

21 January 2018

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Evidence for a susceptibility locus for panic disorder near the catechol-O-methyltransferase gene on chromosome 22

21 January 2018

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No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder

21 January 2018

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Linkage genome scan for loci predisposing to panic disorder or agoraphobia

21 January 2018

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Excess of High Activity Monoamine Oxidase A Gene Promoter Alleles in Female Patients with Panic Disorder

21 January 2018

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Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease

21 January 2018

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Molecular Forms and Regional Distribution of Cholecystokinin in the Central Nervous System

21 January 2018

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7 January 2021

Classification and function of CCK receptors

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7 January 2021

Replication of action of cholecystokinin tetrapeptide in panic disorder: clinical and behavioral findings

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7 January 2021

Effect of the selective serotonin reuptake inhibitor fluvoxamine on CCK-4 induced panic attacks

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7 January 2021

Imipramine antagonism of the panicogenic effects of cholecystokinin tetrapeptide in panic disorder patients

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7 January 2021

A placebo-controlled trial of L-365,260, a CCKB antagonist, in panic disorder

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7 January 2021

Extra-hippocampal projections of CCK neurons of the hippocampus and subiculum

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7 January 2021

The distribution of thalamic projection neurons containing cholecystokinin messenger RNA, using in situ hybridization histochemistry and retrograde labeling.

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7 January 2021

Expression of cholecystokinin mRNA in corticothalamic projecting neurons: a combined fluorescence in situ hybridization and retrograde tracing study in the ventrolateral thalamus of the rat

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7 January 2021

Influence of clonidine on psychopathological, endocrine and respiratory effects of cholecystokinin tetrapeptide in patients with panic disorder

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7 January 2021

Effects of repetitive transcranial magnetic stimulation (rTMS) on panic attacks induced by cholecystokinin-tetrapeptide (CCK-4)

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7 January 2021

Brain cholecystokinin tetrapeptide levels are increased in a rat model of anxiety.

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7 January 2021

Autoradiographic localization of cholecystokinin receptors in rodent brain

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7 January 2021

Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear.

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7 January 2021

Activation of amygdala cholecystokininB receptors potentiates the acoustic startle response in the rat.

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7 January 2021

CCK receptor antagonists in animal models of anxiety: comparison between exploration tests, conflict procedures and a model based on defensive behaviours.

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7 January 2021

Neuroanatomical circuits modulating fear and anxiety behaviors.

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7 January 2021

Acute and chronic role of 5-HT3 neuronal system on behavioral and neuroendocrine changes induced by intravenous cholecystokinin tetrapeptide administration in humans

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7 January 2021

Cholecystokinin-8 increases K(+)-evoked [3H] gamma-aminobutyric acid release in slices from various brain areas

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7 January 2021

Effect of local cholecystokinin-8 administration on extracellular levels of amino acids and glycolytic products monitored by in vivo microdialysis in the fronto-parietal cortex of the rat

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7 January 2021

The role of the beta-noradrenergic system in cholecystokinin-tetrapeptide-induced panic symptoms

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7 January 2021

Elevated plasma levels of neuropeptide Y in patients with panic disorder

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7 January 2021

Possible association of a cholecystokinin promotor polymorphism (CCK-36CT) with panic disorder

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7 January 2021

An association of NAG levels and a mutation of the CCK gene in panic disorder patients

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7 January 2021

Gene variations in the cholecystokinin system in patients with panic disorder

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7 January 2021

Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder

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7 January 2021

Missense mutation of the cholecystokinin B receptor gene: lack of association with panic disorder

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7 January 2021

Identifiers

DOI

10.1002/DA.21919

1 reference

1 August 2017

1 reference

PubMed ID

22553078