(Q34274077)

1 August 2017

Engineering the third wave of biocatalysis (English)

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1 August 2017

1

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ORCID Public Data File 2021

1 August 2017

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author name string

G W Huisman

2

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1 August 2017

R J Kazlauskas

3

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1 August 2017

S Lutz

4

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1 August 2017

J C Moore

5

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1 August 2017

K Robins

6

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1 August 2017

language of work or name

English

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publication date

9 May 2012

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1 August 2017

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1 August 2017

485

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1 August 2017

185-194

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1 August 2017

7397

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https://scigraph.springernature.com/pub.10.1038/nature11117

1 August 2017

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cites work

Recombinant polycistronic structure of hydantoinase process genes in Escherichia coli for the production of optically pure D-amino acids.

1 reference

12 December 2020

Conversion of Pyruvate Decarboxylase into an Enantioselective Carboligase with Biosynthetic Potential

1 reference

12 December 2020

Highly active mutants of carbonyl reductase S1 with inverted coenzyme specificity and production of optically active alcohols

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12 December 2020

Advances in the enzymatic reduction of ketones

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12 December 2020

Manufacturing molecules through metabolic engineering

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12 December 2020

Engineering delta 9-16:0-acyl carrier protein (ACP) desaturase specificity based on combinatorial saturation mutagenesis and logical redesign of the castor delta 9-18:0-ACP desaturase

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12 December 2020

A combination of in vivo selection and cell sorting for the identification of enantioselective biocatalysts.

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12 December 2020

Protein tolerance to random amino acid change

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12 December 2020

Cloning, nucleotide sequence and expression of a hydantoinase and carbamoylase gene from Arthrobacter aurescens DSM 3745 in Escherichia coli and comparison with the corresponding genes from Arthrobacter aurescens DSM 3747.

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12 December 2020

Selection and evolution of enzymes from a partially randomized non-catalytic scaffold

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12 December 2020

Characterization of Bacillus thuringiensis L-isoleucine dioxygenase for production of useful amino acids

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12 December 2020

Beyond directed evolution--semi-rational protein engineering and design

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12 December 2020

Styrene biosynthesis from glucose by engineered E. coli

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12 December 2020

Creation of a productive, highly enantioselective nitrilase through gene site saturation mutagenesis (GSSM).

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12 December 2020

In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting

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12 December 2020

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

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12 December 2020

Metabolic engineering of poly(3-hydroxyalkanoates): from DNA to plastic

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12 December 2020

Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates

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12 December 2020

Metagenomics and industrial applications

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12 December 2020

Engineering the nanoparticle-protein interface: applications and possibilities

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12 December 2020

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution

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12 December 2020

Mutations in distant residues moderately increase the enantioselectivity of Pseudomonas fluorescens esterase towards methyl 3bromo-2-methylpropanoate and ethyl 3phenylbutyrate

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12 December 2020

Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst

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12 December 2020

High-resolution mapping of protein sequence-function relationships

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12 December 2020

ProTherm, version 4.0: thermodynamic database for proteins and mutants

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12 December 2020

Dispelling the myths--biocatalysis in industrial synthesis

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12 December 2020

Biotechnology for the acceleration of carbon dioxide capture and sequestration

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12 December 2020

Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents

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12 December 2020

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

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12 December 2020

Improving catalytic function by ProSAR-driven enzyme evolution.

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12 December 2020

Directed evolution of metabolic pathways in microbial populations. I. Modification of the acid phosphatase pH optimum in S. cerevisiae.

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12 December 2020

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

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12 December 2020

Directed enzyme evolution via small and effective neutral drift libraries

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12 December 2020

Why highly expressed proteins evolve slowly

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12 December 2020

Advances in biocatalytic synthesis of pharmaceutical intermediates

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12 December 2020

Kemp elimination catalysts by computational enzyme design

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12 December 2020

Wiring-up hydrogenase with single-walled carbon nanotubes

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12 December 2020

Additivity of mutational effects in proteins

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12 December 2020

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

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12 December 2020

Rational assignment of key motifs for function guides in silico enzyme identification

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12 December 2020

Initial sequencing and comparative analysis of the mouse genome

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12 December 2020

Thermostability reinforcement through a combination of thermostability-related mutations of N-carbamyl-D-amino acid amidohydrolase

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12 December 2020

Single-cell high-throughput screening to identify enantioselective hydrolytic enzymes.

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12 December 2020

Sitagliptin manufacture: a compelling tale of green chemistry, process intensification, and industrial asymmetric catalysis.

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12 December 2020

Engineering an enzyme by site-directed mutagenesis to be resistant to chemical oxidation

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12 December 2020

Application of designed enzymes in organic synthesis

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12 December 2020

Combinatorial and computational challenges for biocatalyst design

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12 December 2020

Directed evolution of an aminoalcohol dehydrogenase for efficient production of double chiral aminoalcohols

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12 December 2020

Creation of a bacterial cell controlled by a chemically synthesized genome

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12 December 2020

Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

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12 December 2020

Directed evolution drives the next generation of biocatalysts

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12 December 2020

Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase

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12 December 2020

Focusing mutations into the P. fluorescens esterase binding site increases enantioselectivity more effectively than distant mutations

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12 December 2020

Finding better protein engineering strategies

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12 December 2020

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

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12 December 2020

Synthetic protein scaffolds provide modular control over metabolic flux.

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12 December 2020

Amplification and assembly of chip-eluted DNA (AACED): a method for high-throughput gene synthesis

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12 December 2020

Biosynthesis of lovastatin analogs with a broadly specific acyltransferase.

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12 December 2020

Natural diversity to guide focused directed evolution

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12 December 2020

Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

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12 December 2020

The synthesis of chiral cyanohydrins by oxynitrilases

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12 December 2020

Metabolic engineering for the microbial production of 1,3-propanediol

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12 December 2020

High levels of bioplastic are produced in fertile transplastomic tobacco plants engineered with a synthetic operon for the production of polyhydroxybutyrate

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12 December 2020

Designed divergent evolution of enzyme function

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12 December 2020

Biochemical retrosynthesis of 2'-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase

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12 December 2020

Biotransformations of steroids

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12 December 2020

Industrial biocatalysis today and tomorrow

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12 December 2020

Constructing and analyzing the fitness landscape of an experimental evolutionary process

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12 December 2020

De novo computational design of retro-aldol enzymes

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12 December 2020

Industrial methods for the production of optically active intermediates

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12 December 2020

Darwinian evolution can follow only very few mutational paths to fitter proteins

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12 December 2020

A system for the continuous directed evolution of biomolecules

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12 December 2020

Industrial biotechnology—the future of green chemistry?

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE11117

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE11117

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Dimensions Publication ID

1 August 2017

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