(Q34279373)

1 August 2017

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles (English)

1 reference

1 August 2017

8

Stuart L Schreiber

1 reference

1 August 2017

Paul A Clemons

1

1 reference

1 August 2017

Nicole E Bodycombe

2

1 reference

1 August 2017

Hyman A Carrinski

3

1 reference

1 August 2017

J Anthony Wilson

4

1 reference

1 August 2017

Alykhan F Shamji

5

1 reference

1 August 2017

Bridget K Wagner

6

1 reference

1 August 2017

Angela N Koehler

7

1 reference

1 August 2017

language of work or name

English

0 references

publication date

18 October 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

1 reference

1 August 2017

107

1 reference

1 August 2017

18787-18792

1 reference

1 August 2017

44

1 reference

Distinct biological network properties between the targets of natural products and disease genes

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Extended-connectivity fingerprints

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Chemoinformatic analysis of combinatorial libraries, drugs, natural products, and molecular libraries small molecule repository

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

The impact of natural products upon modern drug discovery.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Application of belief theory to similarity data fusion for use in analog searching and lead hopping

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Cheminformatics analysis of natural products: lessons from nature inspiring the design of new drugs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

ChemBank: a small-molecule screening and cheminformatics resource database

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Discovery of chemical reactions through multidimensional screening

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

A pipeline for ligand discovery using small-molecule microarrays

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Olefin-metathesis catalysts for the preparation of molecules and materials (Nobel Lecture).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

A robust small-molecule microarray platform for screening cell lysates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Relationships between Molecular Complexity, Biological Activity, and Structural Diversity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Navigating chemical space for biology and medicine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

A library of spirooxindoles based on a stereoselective three-component coupling reaction.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Molecular complexity and its impact on the probability of finding leads for drug discovery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

The properties of known drugs. 1. Molecular frameworks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Analysis of the Structure-Activity Relationship of the Sulfonamide Drugs Using Substituent Constants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012741107

Escape from flatland: increasing saturation as an approach to improving clinical success.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012741107

Using extended-connectivity fingerprints with Laplacian-modified Bayesian analysis in high-throughput screening follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012741107

Enantioselective Brønsted acid-catalyzed N-acyliminium cyclization cascades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012741107

Highly flexible synthesis of chiral azacycles via iridium-catalyzed hydrogenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012741107

Searching for new reactivity (Nobel lecture).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973913

SUBSTITUENT CONSTANTS FOR ALIPHATIC FUNCTIONS OBTAINED FROM PARTITION COEFFICIENTS

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20956335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1012741107

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference