(Q34280406)

1 August 2017

title

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production (English)

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1 August 2017

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Citron M

1

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1 August 2017

Oltersdorf T

2

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1 August 2017

Haass C

3

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1 August 2017

McConlogue L

4

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1 August 2017

Hung AY

5

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1 August 2017

Seubert P

6

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1 August 2017

Vigo-Pelfrey C

7

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1 August 2017

Lieberburg I

8

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1 August 2017

Selkoe DJ

9

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1 August 2017

language of work or name

English

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publication date

1 December 1992

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1 August 2017

17 December 1992

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1465129

29 September 2022

number of pages

3

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inferred from page(s)

published in

Nature

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1 August 2017

volume

360

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1 August 2017

issue

6405

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1 August 2017

page(s)

672-674

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 August 2017

cites work

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7 January 2021

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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7 January 2021

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

1 reference

7 January 2021

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

1 reference

7 January 2021

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

7 January 2021

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

7 January 2021

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

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7 January 2021

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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7 January 2021

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

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7 January 2021

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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7 January 2021

Cleavage of amyloid beta peptide during constitutive processing of its precursor

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7 January 2021

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

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7 January 2021

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

7 January 2021

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type

1 reference

7 January 2021

Identifiers

DOI

10.1038/360672A0

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Dimensions Publication ID

1 August 2017

1000102496

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