(Q34297058)

1 August 2017

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title

Replication-selective virotherapy for cancer: Biological principles, risk management and future directions (English)

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1 August 2017

Kirn D

1

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1 August 2017

Martuza RL

series ordinal

2

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1 August 2017

Zwiebel J

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 July 2001

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

7

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1 August 2017

page(s)

781-787

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Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

1 August 2017

cites work

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Replication-selective microbiological agents: fighting cancer with targeted germ warfare

21 January 2018

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21 January 2018

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Conditionally replicating herpes vectors for cancer therapy

21 January 2018

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Reovirus as a novel oncolytic agent

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Poxvirus vectors: orphaned and underappreciated

21 January 2018

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Newcastle disease virus as an antineoplastic agent: induction of tumor necrosis factor-alpha and augmentation of its cytotoxicity

21 January 2018

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Reovirus therapy of tumors with activated Ras pathway

21 January 2018

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Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

21 January 2018

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Antineoplasic activity of parvoviruses

21 January 2018

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

21 January 2018

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

21 January 2018

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A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

21 January 2018

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Intergeneric poliovirus recombinants for the treatment of malignant glioma

21 January 2018

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A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma

21 January 2018

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The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

21 January 2018

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A model for tumor suppression using H-1 parvovirus

21 January 2018

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Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models

21 January 2018

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Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas

21 January 2018

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

21 January 2018

1 reference

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

21 January 2018

1 reference

Vaccinia as a vector for tumor-directed gene therapy: biodistribution of a thymidine kinase-deleted mutant

21 January 2018

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Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma

21 January 2018

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Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.

21 January 2018

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Adenovirus type 5 viral particles pseudotyped with mutagenized fiber proteins show diminished infectivity of coxsackie B-adenovirus receptor-bearing cells

21 January 2018

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Identification of a conserved receptor-binding site on the fiber proteins of CAR-recognizing adenoviridae

21 January 2018

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Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?

21 January 2018

1 reference

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

21 January 2018

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

21 January 2018

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

21 January 2018

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Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses

21 January 2018

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Replication-restricted vaccinia as a cytokine gene therapy vector in cancer: persistent transgene expression despite antibody generation.

21 January 2018

1 reference

A phase II study on the postsurgical management of Stage II malignant melanoma with a Newcastle disease virus oncolysate

21 January 2018

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Postoperative active specific immunization in curatively resected colorectal cancer patients with a virus-modified autologous tumor cell vaccine

21 January 2018

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In vitro and clinical characterisation of a newcastle disease virus-modified autologous tumour cell vaccine for treatment of colorectal cancer patients

21 January 2018

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Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects

21 January 2018

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Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus

21 January 2018

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Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector

21 January 2018

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Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma.

21 January 2018

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Characteristics of reovirus-mediated chemoimmunotherapy of murine L1210 leukemia

21 January 2018

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Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

21 January 2018

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Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector

21 January 2018

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Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer

21 January 2018

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A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

21 January 2018

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Highly efficient transduction and expression of cytokine genes in human tumor cells by means of autonomous parvovirus vectors; generation of antitumor responses in recipient mice

21 January 2018

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Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression

21 January 2018

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Use of preferentially replicating bacteria for the treatment of cancer

21 January 2018

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An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

21 January 2018

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7 January 2021

Transcriptional targeting of herpes simplex virus for cell-specific replication

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7 January 2021

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

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7 January 2021

The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle

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7 January 2021

Gene therapy for cancer

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7 January 2021

Identifiers

DOI

10.1038/89901

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Dimensions Publication ID

1 August 2017

1014409607

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