(Q34305706)

1 August 2017

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title

Role of serine/threonine protein phosphatase 2A in cancer (English)

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1 August 2017

Schönthal AH

1

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PubMed ID

11448528

1 August 2017

language of work or name

English

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publication date

1 September 2001

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1 August 2017

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1 August 2017

170

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1 August 2017

1-13

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1 August 2017

1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

1 August 2017

1 reference

7 January 2021

Oncogenes and cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Signaling--2000 and beyond

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Phosphatases and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

CDC25 phosphatases as potential human oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

PTEN: life as a tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The multiple roles of PTEN in tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Cell cycle arrest by the PTEN tumor suppressor is target cell specific and may require protein phosphatase activity

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein serine/threonine phosphatases--new avenues for cell regulation

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Regulation of protein kinase cascades by protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatase 2A: a panoply of enzymes.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphorylation and protein phosphatases. De Panne, Belgium, September 19-24, 1999.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Novel protein serine/threonine phosphatases: variety is the spice of life

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein dephosphorylation and the intracellular control of the cell number.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Calcineurin regulation of the mammalian G0/G1 checkpoint element, cyclin dependent kinase 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

FIN13, a novel growth factor-inducible serine-threonine phosphatase which can inhibit cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Serine/threonine protein phosphatases

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Saccharomyces cerevisiae homologs of mammalian B and B' subunits of protein phosphatase 2A direct the enzyme to distinct cellular functions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Flicking the switches: phosphorylation of serine/threonine protein phosphatases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Physiologic importance of protein phosphatase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

AP-1 function and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Regulation of gene expression by serine/threonine protein phosphatases

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Signal transduction through MAP kinase cascades

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Okadaic acid and phorbol esters: comparative effects of these tumor promoters on cell transformation, intercellular communication and differentiation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The tumor promoters 12-O-tetradecanoylphorbol-13-acetate and okadaic acid differ in toxicity, mitogenic activity and induction of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The non-phorbol ester tumor promoter okadaic acid does not promote morphological transformation or inhibit junctional communication in hamster embryo cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Regulation by tumour antigens defines a role for PP2A in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Telomerase activity, cell proliferation, and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Reduction of Ha-ras-induced cellular transformation by elevated expression of protein phosphatase type 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatase 2A is required for the initiation of chromosomal DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Cell cycle targets of Ras/Raf signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Flat reversion by okadaic acid of raf and ret-II transformants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

A positive role for the PP2A catalytic subunit in Wnt signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Distinct roles for PP1 and PP2A in phosphorylation of the retinoblastoma protein. PP2a regulates the activities of G(1) cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Negative regulation of mitosis by the fission yeast protein phosphatase ppa2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Inhibition of cdc2 activation by INH/PP2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Type 2A protein phosphatase, the complex regulator of numerous signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

The SIT4 protein phosphatase functions in late G1 for progression into S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Alterations of the PPP2R1B gene in human lung and colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Absence of PPP2R1B gene alterations in primary ovarian cancers

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Identification by differential display of a protein phosphatase-2A regulatory subunit preferentially expressed in malignant melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatases limit tumor motility

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Regulation of cytoskeletal organization in tumor cells by protein phosphatases-1 and -2A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

Protein phosphatase-2A association with microtubules and its role in restricting the invasiveness of human head and neck squamous cell carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900561-4

7 January 2021

10.1016/S0304-3835(01)00561-4

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11448528