(Q34314899)

English

Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors

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scholarly article

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Europe PubMed Central

1 August 2017

Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors (English)

1 reference

Europe PubMed Central

1 August 2017

1 reference

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author name string

Z Ping Lin

1

1 reference

Europe PubMed Central

1 August 2017

Michael F Belcourt

2

1 reference

Europe PubMed Central

1 August 2017

Joseph G Cory

3

1 reference

Europe PubMed Central

1 August 2017

Alan C Sartorelli

4

1 reference

Europe PubMed Central

1 August 2017

language of work or name

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publication date

19 April 2004

1 reference

Europe PubMed Central

1 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

1 August 2017

279

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Europe PubMed Central

1 August 2017

27030-27038

1 reference

Europe PubMed Central

1 August 2017

26

1 reference

Europe PubMed Central

1 August 2017

Reduction of Ribonucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

S-Phase-specific expression of mammalian ribonucleotide reductase R1 and R2 subunit mRNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

A ribonucleotide reductase gene is a transcriptional target of p53 and p73

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Didox (a novel ribonucleotide reductase inhibitor) overcomes Bcl-2 mediated radiation resistance in prostate cancer cell line PC-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Phleomycin resistance as a dominant selectable marker in CHO cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Identification and isolation of the gene encoding the small subunit of ribonucleotide reductase from Saccharomyces cerevisiae: DNA damage-inducible gene required for mitotic viability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

DNA damage induction of ribonucleotide reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Induction of the mouse ribonucleotide reductase R1 and R2 genes in response to DNA damage by UV light

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

DNA repair: enzymatic mechanisms and relevance to drug response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402056200

21 January 2018

Identifiers

10.1074/JBC.M402056200

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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