(Q34336256)

1 August 2017

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title

Chemical construction of immunotoxins. (English)

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1 August 2017

2

Vitetta ES

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1 August 2017

1

Ghetie V

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1 August 2017

publication date

1 July 2001

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1 August 2017

published in

Molecular Biotechnology

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1 August 2017

volume

18

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1 August 2017

issue

3

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1 August 2017

page(s)

251-268

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Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli.

1 August 2017

cites work

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12 December 2020

Purification of ricin A1, A2, and B chains and characterization of their toxicity.

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12 December 2020

Preparation of F(ab')2 fragments from mouse IgG of various subclasses

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12 December 2020

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

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12 December 2020

Pseudomonas exotoxin-based immunotoxins containing the antibody LL2 or LL2-Fab' induce regression of subcutaneous human B-cell lymphoma in mice

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12 December 2020

More useful maleimide compounds for the conjugation of Fab' to horseradish peroxidase through thiol groups in the hinge

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12 December 2020

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

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12 December 2020

A new reagent which may be used to introduce sulfhydryl groups into proteins, and its use in the preparation of conjugates for immunoassay

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12 December 2020

Comparison of two anti-Thy 1.1-abrin A-chain immunotoxins prepared with different cross-linking agents: antitumor effects, in vivo fate, and tumor cell mutants.

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12 December 2020

Immunotoxins in the therapy of cancer: from bench to clinic

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12 December 2020

New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.

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12 December 2020

Pokeweed antiviral protein: ribosome inactivation and therapeutic applications

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12 December 2020

The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin

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12 December 2020

Immunotoxin therapy for cancer

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12 December 2020

Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages

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12 December 2020

Immunotoxin-mediated elimination of clonogenic tumor cells in the presence of human bone marrow.

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12 December 2020

The GLP large scale preparation of immunotoxins containing deglycosylated ricin A chain and a hindered disulfide bond.

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12 December 2020

Immunotoxins: magic bullets or misguided missiles?

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12 December 2020

Antitumor activity of a thioether-linked immunotoxin: OVB3-PE.

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12 December 2020

Production of a pokeweed antiviral protein (PAP)-containing immunotoxin, B43-PAP, directed against the CD19 human B lineage lymphoid differentiation antigen in highly purified form for human clinical trials

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12 December 2020

On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice

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12 December 2020

Antitumor activity of Fab' and IgG-anti-CD22 immunotoxins in disseminated human B lymphoma grown in mice with severe combined immunodeficiency disease: effect on tumor cells in extranodal sites

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12 December 2020

Modification of the carbohydrate in ricin with metaperiodate-cyanoborohydride mixtures. Effects on toxicity and in vivo distribution

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12 December 2020

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

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12 December 2020

Recent developments in immunotoxin therapy

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12 December 2020

Pokeweed antiviral protein

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12 December 2020

The galactose-binding sites of the cytotoxic lectin ricin can be chemically blocked in high yield with reactive ligands prepared by chemical modification of glycopeptides containing triantennary N-linked oligosaccharides

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12 December 2020

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy

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12 December 2020

Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers

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12 December 2020

Characterization of RFB4-Pseudomonas exotoxin A immunotoxins targeted to CD22 on B-cell malignancies

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12 December 2020

Clinical trials of targeted toxins

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12 December 2020

A brief survey of methods for preparing protein conjugates with dyes, haptens, and cross-linking reagents

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12 December 2020

Immunotoxins against cancer

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12 December 2020

Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains.

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12 December 2020

Large scale preparation of immunotoxins constructed with the Fab' fragment of IgG1 murine monoclonal antibodies and chemically deglycosylated ricin A chain.

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12 December 2020

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12 December 2020

Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent

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12 December 2020

The in vivo anti-tumor activity of immunotoxins containing two versus one deglycosylated ricin A chains

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12 December 2020

Disseminated or localized growth of a human B-cell tumor (Daudi) in SCID mice

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12 December 2020

An immunotoxin prepared with blocked ricin: a natural plant toxin adapted for therapeutic use

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12 December 2020

Immunotoxin therapy of lymphoid neoplasms.

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12 December 2020

Identifiers

DOI

10.1385/MB:18:3:251

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Dimensions Publication ID

1 August 2017

1024239777

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